[HTML][HTML] Molecular Determinants of β-Lactam Resistance in Methicillin-Resistant Staphylococcus aureus (MRSA): An Updated Review

H Lade, JS Kim - Antibiotics, 2023 - mdpi.com
The development of antibiotic resistance in Staphylococcus aureus, particularly in methicillin-
resistant S. aureus (MRSA), has become a significant health concern worldwide. The …

Bacterial cell mechanics

GK Auer, DB Weibel - Biochemistry, 2017 - ACS Publications
Cellular mechanical properties play an integral role in bacterial survival and adaptation.
Historically, the bacterial cell wall and, in particular, the layer of polymeric material called the …

Staphylococcus aureus cell wall maintenance – the multifaceted roles of peptidoglycan hydrolases in bacterial growth, fitness, and virulence

M Wang, G Buist, JM van Dijl - FEMS microbiology reviews, 2022 - academic.oup.com
Staphylococcus aureus is an important human and livestock pathogen that is well-protected
against environmental insults by a thick cell wall. Accordingly, the wall is a major target of …

Cell shape dynamics during the staphylococcal cell cycle

JM Monteiro, PB Fernandes, F Vaz, AR Pereira… - Nature …, 2015 - nature.com
Staphylococcus aureus is an aggressive pathogen and a model organism to study cell
division in sequential orthogonal planes in spherical bacteria. However, the small size of …

AFM in cellular and molecular microbiology

YF Dufrêne, A Viljoen, J Mignolet… - Cellular …, 2021 - Wiley Online Library
The unique capabilities of the atomic force microscope (AFM), including super‐resolution
imaging, piconewton force‐sensitivity, nanomanipulation and ability to work under …

β-Lactams against the Fortress of the Gram-Positive Staphylococcus aureus Bacterium

JF Fisher, S Mobashery - Chemical reviews, 2020 - ACS Publications
The biological diversity of the unicellular bacteria—whether assessed by shape, food,
metabolism, or ecological niche—surely rivals (if not exceeds) that of the multicellular …

Peptidoglycan

M Pazos, K Peters - Bacterial cell walls and membranes, 2019 - Springer
The peptidoglycan sacculus is a net-like polymer that surrounds the cytoplasmic membrane
in most bacteria. It is essential to maintain the bacterial cell shape and protect from turgor …

β-Lactam resistance mechanisms: Gram-positive bacteria and Mycobacterium tuberculosis

JF Fisher, S Mobashery - Cold Spring …, 2016 - perspectivesinmedicine.cshlp.org
The value of the β-lactam antibiotics for the control of bacterial infection has eroded with
time. Three Gram-positive human pathogens that were once routinely susceptible to β …

Strength of bacterial adhesion on nanostructured surfaces quantified by substrate morphometry

C Spengler, F Nolle, J Mischo, T Faidt, S Grandthyll… - Nanoscale, 2019 - pubs.rsc.org
Microbial adhesion and the subsequent formation of resilient biofilms at surfaces are
decisively influenced by substrate properties, such as the topography. To date, studies that …

The role of GpsB in Staphylococcus aureus cell morphogenesis

SF Costa, BM Saraiva, H Veiga, LB Marques… - Mbio, 2024 - journals.asm.org
For decades, cells of the Gram-positive bacterial pathogen Staphylococcus aureus were
thought to lack a dedicated elongation machinery. However, S. aureus cells were recently …