Filopodia are dynamic, narrow, plasma membrane protrusions filled with bundled actin
filaments. Fresh actin monomers are incorporated at the tips furthest away from the cell …

Collective cell migration is the coordinated movement of a physically connected group of
cells and is a prominent driver of development and metastasis. Interactions between cells …

Filopodia are adhesive cellular protrusions specialized in the detection of extracellular
matrix (ECM)-derived cues. Although ECM engagement at focal adhesions is known to …

Comprehensive analysis of cellular dynamics during the process of morphogenesis is
fundamental to understanding the principles of animal development. Despite recent …

A signature feature of the animal kingdom is the presence of epithelia: sheets of polarized
cells that both insulate the organism from its environment and mediate interactions with it …

Abstract Morphogenesis of the Central Nervous System (CNS) is a complex process that
obeys precise architectural rules. Yet, the mechanisms dictating these rules remain …

Actomyosin networks provide the major contractile machinery for regulating cell and tissue
morphogenesis during development. These networks undergo dynamic rearrangements …

Drosophila is an important model for studying heart development and disease. Yet, single-
cell transcriptomic data of its develo** heart have not been performed. Here, we report …

Development encapsulates the morphogenesis of an organism from a single fertilized cell to
a functional adult. A critical part of development is the specification of organ forms. Beyond …

Epithelial cells dynamically self-organize in response to extracellular spatial cues relayed by
cell-surface receptors. During convergent extension in Drosophila, Toll-related receptors …