Hybrid exosomes, exosome-like nanovesicles and engineered exosomes for therapeutic applications

J Mondal, S Pillarisetti, V Junnuthula, M Saha… - Journal of Controlled …, 2023 - Elsevier
Exosomes are endosome-derived nanovesicles involved in cellular communication. They
are natural nanocarriers secreted by various cells, making them suitable candidates for …

[HTML][HTML] Curcumin and cancer

A Giordano, G Tommonaro - Nutrients, 2019 - mdpi.com
Curcumin, a polyphenol extracted from Curcuma longa in 1815, has gained attention from
scientists worldwide for its biological activities (eg, antioxidant, anti-inflammatory …

[HTML][HTML] Exosome-based drug delivery: translation from bench to clinic

HB Koh, HJ Kim, SW Kang, TH Yoo - Pharmaceutics, 2023 - mdpi.com
Exosome-based drug delivery is emerging as a promising field with the potential to
revolutionize therapeutic interventions. Exosomes, which are small extracellular vesicles …

Surface functionalization of exosomes for target-specific delivery and in vivo imaging & tracking: Strategies and significance

S Salunkhe, M Basak, D Chitkara, A Mittal - Journal of Controlled …, 2020 - Elsevier
Exosomes are natural nanovesicles excreted by many cells for intercellular communication
and for transfer of materials including proteins, nucleic acids and even synthetic therapeutic …

Antiviral effect of phytochemicals from medicinal plants: Applications and drug delivery strategies

S Ben-Shabat, L Yarmolinsky, D Porat… - Drug delivery and …, 2020 - Springer
Viral infections affect three to five million patients annually. While commonly used antivirals
often show limited efficacy and serious adverse effects, herbal extracts have been in use for …

[HTML][HTML] Extracellular vesicles in nanomedicine and regenerative medicine: a review over the last decade

S Moghassemi, A Dadashzadeh, MJ Sousa, H Vlieghe… - Bioactive materials, 2024 - Elsevier
Small extracellular vesicles (sEVs) are known to be secreted by a vast majority of cells.
These sEVs, specifically exosomes, induce specific cell-to-cell interactions and can activate …

Extracellular vesicles in cancer drug resistance: roles, mechanisms, and implications

Q Yang, J Xu, J Gu, H Shi, J Zhang, J Zhang… - Advanced …, 2022 - Wiley Online Library
Extracellular vesicles (EVs) are cell‐derived nanosized vesicles that mediate cell‐to‐cell
communication via transporting bioactive molecules and thus are critically involved in …

Extracellular vesicles as a drug delivery system: A systematic review of preclinical studies

PEM de Castilla, L Tong, C Huang, AM Sofias… - Advanced drug delivery …, 2021 - Elsevier
During the past decades, extracellular vesicles (EVs) have emerged as an attractive drug
delivery system. Here, we assess their pre-clinical applications, in the form of a systematic …

Emerging prospects of exosomes for cancer treatment: from conventional therapy to immunotherapy

GH Nam, Y Choi, GB Kim, S Kim, SA Kim… - Advanced …, 2020 - Wiley Online Library
Exosomes are a class of extracellular vesicles of around 100 nm in diameter that are
secreted by most cells and contain various bioactive molecules reflecting their cellular origin …

[HTML][HTML] Exosomes as naturally occurring vehicles for delivery of biopharmaceuticals: insights from drug delivery to clinical perspectives

A Butreddy, N Kommineni, N Dudhipala - Nanomaterials, 2021 - mdpi.com
Exosomes as nanosized vesicles are emerging as drug delivery systems for therapeutics
owing to their natural origin, their ability to mediate intercellular communication, and their …