Quantitative phase imaging techniques for the study of cell pathophysiology: from principles to applications
A cellular-level study of the pathophysiology is crucial for understanding the mechanisms
behind human diseases. Recent advances in quantitative phase imaging (QPI) techniques …
behind human diseases. Recent advances in quantitative phase imaging (QPI) techniques …
Live-cell mass profiling: an emerging approach in quantitative biophysics
Cell mass, volume and growth rate are tightly controlled biophysical parameters in cellular
development and homeostasis, and pathological cell growth defines cancer in metazoans …
development and homeostasis, and pathological cell growth defines cancer in metazoans …
High-resolution 3D refractive index microscopy of multiple-scattering samples from intensity images
Optical diffraction tomography (ODT) reconstructs a sample's volumetric refractive index (RI)
to create high-contrast, quantitative 3D visualizations of biological samples. However …
to create high-contrast, quantitative 3D visualizations of biological samples. However …
Real‐time stain‐free classification of cancer cells and blood cells using interferometric phase microscopy and machine learning
We present a method for real‐time visualization and automatic processing for detection and
classification of untreated cancer cells in blood during stain‐free imaging flow cytometry …
classification of untreated cancer cells in blood during stain‐free imaging flow cytometry …
Quantitative phase imaging for medical diagnosis
Optical microscopy is an indispensable diagnostic tool in modern healthcare. As a prime
example, pathologists rely exclusively on light microscopy to investigate tissue morphology …
example, pathologists rely exclusively on light microscopy to investigate tissue morphology …
Quantitative phase microscopy of biological samples using a portable interferometer
NT Shaked - Optics letters, 2012 - opg.optica.org
This Letter presents the τ interferometer, a portable and inexpensive device for obtaining
spatial interferograms of microscopic biological samples without the strict stability and the …
spatial interferograms of microscopic biological samples without the strict stability and the …
Resolution enhancement in quantitative phase microscopy
Quantitative phase microscopy (QPM), a technique combining phase imaging and
microscopy, enables visualization of the 3D topography in reflective samples, as well as the …
microscopy, enables visualization of the 3D topography in reflective samples, as well as the …
Generalized cell morphological parameters based on interferometric phase microscopy and their application to cell life cycle characterization
We present analysis tools which are formulated using wide-field interferometric phase
microscopy measurements, and show their ability to uniquely quantify the life cycle of live …
microscopy measurements, and show their ability to uniquely quantify the life cycle of live …
Measurement of Single Cell Refractive Index, Dry Mass, Volume, and Density<? format?> Using a Transillumination Microscope
Phase contrast microscopy has become ubiquitous in the field of biology, particularly in
qualitative investigations of cellular morphology. However, the use of quantitative phase …
qualitative investigations of cellular morphology. However, the use of quantitative phase …
Quantitative refractive index distribution of single cell by combining phase-shifting interferometry and AFM imaging
Q Zhang, L Zhong, P Tang, Y Yuan, S Liu, J Tian… - Scientific reports, 2017 - nature.com
Cell refractive index, an intrinsic optical parameter, is closely correlated with the intracellular
mass and concentration. By combining optical phase-shifting interferometry (PSI) and atomic …
mass and concentration. By combining optical phase-shifting interferometry (PSI) and atomic …