Triggering antitumoural drug release and gene expression by magnetic hyperthermia

M Moros, J Idiago-López, L Asín… - Advanced drug delivery …, 2019 - Elsevier
Magnetic nanoparticles (MNPs) are promising tools for a wide array of biomedical
applications. One of their most outstanding properties is the ability to generate heat when …

TRAIL in oncology: From recombinant TRAIL to nano-and self-targeted TRAIL-based therapies

H Dianat-Moghadam, M Heidarifard, A Mahari… - Pharmacological …, 2020 - Elsevier
TNF-related apoptosis-inducing ligand (TRAIL) selectively induces the apoptosis pathway in
tumor cells leading to tumor cell death. Because TRAIL induction can kill tumor cells, cancer …

Enhanced anticancer efficacy of TRAIL-conjugated and odanacatib-loaded PLGA nanoparticles in TRAIL resistant cancer

TTK Nguyen, SM Woo, SU Seo, A Banstola, H Kim… - Biomaterials, 2025 - Elsevier
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) demonstrates unique
characteristics in anticancer therapies as it selectively induces apoptosis in cancer cells …

Biomimetic nanoparticles blocking autophagy for enhanced chemotherapy and metastasis inhibition via reversing focal adhesion disassembly

Y Shi, G Lin, H Zheng, D Mu, H Chen, Z Lu… - Journal of …, 2021 - Springer
Background Autophagy is a conserved catabolic process, which plays an important role in
regulating tumor cell motility and degrading protein aggregates. Chemotherapy-induced …

Mitoxantrone Combined with Engineered TRAIL‐Nanovesicles for Enhanced Cancer Immunotherapy Via Converting Apoptosis into Pyroptosis

Y Wang, B Niu, Y Tian, H Lan, Z Zhou… - Advanced …, 2024 - Wiley Online Library
Pyroptosis, a highly inflammatory form of programmed cell death, has emerged as a
promising target for cancer immunotherapy. However, in the context of pyroptosis execution …

Photo-excitable hybrid nanocomposites for image-guided photo/TRAIL synergistic cancer therapy

G Lin, Y Zhang, C Zhu, C Chu, Y Shi, X Pang, E Ren… - Biomaterials, 2018 - Elsevier
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) can induce apoptosis in
cancer cells without toxicity to normal cells. However, the efficiency is greatly limited by its …

Enhancing the antitumor activity of an engineered TRAIL-coated oncolytic adenovirus for treating acute myeloid leukemia

Z Wang, W Liu, L Wang, P Gao, Z Li, J Wu… - … and Targeted Therapy, 2020 - nature.com
The use of oncolytic viruses has emerged as a promising therapeutic approach due to the
features of these viruses, which selectively replicate and destroy tumor cells while sparing …

Self-assembled metal-organic nanoparticles for multimodal imaging-guided photothermal therapy of hepatocellular carcinoma

Z Shi, C Chu, Y Zhang, Z Su, H Lin… - Journal of …, 2018 - ingentaconnect.com
Hepatocellular carcinoma (HCC) is a high incidence of disease and the high recurrence rate
is a major limitation for HCC treatment. To resolve such a challenge, multimodal imaging …

[HTML][HTML] Innovative nanomedicine delivery: targeting tumor microenvironment to defeat drug resistance

W Meng, L Huang, J Guo, Q **n, J Liu, Y Hu - Pharmaceutics, 2024 - mdpi.com
Nanodrug delivery systems have revolutionized tumor therapy like never before. By
overcoming the complexity of the tumor microenvironment (TME) and bypassing drug …

[HTML][HTML] Functional probes for cardiovascular molecular imaging

Y Zeng, J Zhu, J Wang, P Parasuraman… - … imaging in medicine …, 2018 - ncbi.nlm.nih.gov
Cardiovascular diseases (CVDs) are a severely threatening disorder and frequently cause
death in industrialized countries, posing critical challenges to modern research and …