T cell responses to cytomegalovirus
Human cytomegalovirus (HCMV) establishes a latent infection that generally remains
asymptomatic in immune-competent hosts for decades but can cause serious illness in …
asymptomatic in immune-competent hosts for decades but can cause serious illness in …
Immunobiology of human cytomegalovirus: from bench to bedside
T Crough, R Khanna - Clinical microbiology reviews, 2009 - Am Soc Microbiol
Following primary infection, human cytomegalovirus (HCMV) establishes lifelong latency
and periodically reactivates without causing symptoms in healthy individuals. In the absence …
and periodically reactivates without causing symptoms in healthy individuals. In the absence …
Cytomegalovirus in hematopoietic stem cell transplant recipients
P Ljungman, M Hakki… - Hematology/Oncology …, 2011 - hemonc.theclinics.com
Human cytomegalovirus (CMV) is a betaherpesvirus in the same family as human
herpesvirus-6 and-7. CMV is a large virus including approximately 200 proteins. CMV has …
herpesvirus-6 and-7. CMV is a large virus including approximately 200 proteins. CMV has …
IL-1R8 is a checkpoint in NK cells regulating anti-tumour and anti-viral activity
Abstract Interleukin-1 receptor 8 (IL-1R8, also known as single immunoglobulin IL-1R-
related receptor, SIGIRR, or TIR8) is a member of the IL-1 receptor (ILR) family with distinct …
related receptor, SIGIRR, or TIR8) is a member of the IL-1 receptor (ILR) family with distinct …
The human cytomegalovirus
Human cytomegalovirus (HCMV), a betaherpesvirus, represents the major infectious cause
of birth defects, as well as an important pathogen for immunocompromised individuals. The …
of birth defects, as well as an important pathogen for immunocompromised individuals. The …
Modulation of innate and adaptive immunity by cytomegaloviruses
The coordinated activities of innate and adaptive immunity are critical for effective protection
against viruses. To counter this, some viruses have evolved sophisticated strategies to …
against viruses. To counter this, some viruses have evolved sophisticated strategies to …
Immune surveillance of cytomegalovirus in tissues
Cytomegalovirus (CMV), a representative member of the Betaherpesvirinae subfamily of
herpesviruses, is common in the human population, but immunocompetent individuals are …
herpesviruses, is common in the human population, but immunocompetent individuals are …
Hierarchical and redundant lymphocyte subset control precludes cytomegalovirus replication during latent infection
Reactivation from latent cytomegalovirus (CMV) infection is often associated with conditions
of immunosuppression and can result in fatal disease. Whether the maintenance of systemic …
of immunosuppression and can result in fatal disease. Whether the maintenance of systemic …
Antigens and immunoevasins: opponents in cytomegalovirus immune surveillance
MJ Reddehase - Nature Reviews Immunology, 2002 - nature.com
CD8+ T cells are the main effector cells for the immune control of cytomegaloviruses. To
subvert this control, human and mouse cytomegaloviruses each encode a set of immune …
subvert this control, human and mouse cytomegaloviruses each encode a set of immune …
Human cytomegalovirus inhibits major histocompatibility complex class II expression by disruption of the Jak/Stat pathway
Human cytomegalovirus (HCMV) is a ubiquitous herpesvirus that is able to persist for
decades in its host. HCMV has evolved protean countermeasures for anti-HCMV cellular …
decades in its host. HCMV has evolved protean countermeasures for anti-HCMV cellular …