Omics-based novel strategies in the diagnosis of endometriosis

M Samare-Najaf, SA Razavinasab… - Critical Reviews in …, 2024 - Taylor & Francis
Endometriosis, an enigmatic and chronic disorder, is considered a debilitating condition
despite being benign. Globally, this gynecologic disorder affects up to 10% of females of …

[HTML][HTML] Systematic review on the DNA methylation role in endometriosis: current evidence and perspectives

B Ducreux, C Patrat, J Firmin, L Ferreux… - Clinical …, 2025 - pmc.ncbi.nlm.nih.gov
Background Endometriosis appears to have a multilayered etiology, with genetic and
epigenetic factors each contributing half of the pathogenesis. The molecular processes that …

Exosomal miR-21-5p derived from endometrial stromal cells promotes angiogenesis by targeting TIMP3 in ovarian endometrial cysts

L Sun, Y Cheng, J Wang, D Wu, L Yuan, X Wei… - Journal of Molecular …, 2024 - Springer
Endometriosis is a multifactorial gynecological disease, with angiogenesis as a key
hallmark. The role of exosomal microRNAs (miRNAs) in endometriosis is not well …

Genome-wide DNA methylation and transcriptome sequencing analyses of lens tissue in an age-related mouse cataract model

Y Hu, D Su, Y Zhang, Y Fu, S Li, X Chen, X Zhang… - PloS one, 2025 - journals.plos.org
DNA methylation is known to be associated with cataracts. In this study, we used a mouse
model and performed DNA methylation and transcriptome sequencing analyses to find …

[HTML][HTML] Therapeutic effects of Huayu Jiedu formula on endometriosis via downregulating GATA 6 expression

W Cheng, J Shan, J Ding, Y Liu, S Sun, L Xu, C Yu - Heliyon, 2024 - cell.com
Abstract Background Endometriosis (EMs) is a common chronic inflammatory disease which
is characterized by multiple clinical symptoms and high recurrence rate due to the absence …

Hypomethylation of IL6ST promotes development of endometriosis by activating JAK2/STAT3 signaling pathway

Y Hu, H Chen, L **, X Chi, J Zhao, Q Cao - PloS one, 2025 - journals.plos.org
Endometriosis is a chronic inflammatory disorder characterized by presence of endometrial
tissue outside the uterine cavity. Immunohistochemical analysis (IHC) revealed markedly …

[HTML][HTML] From Environmental Exposure Risk to Epigenetic Factors: What Role Do They Play in the Etiology of Endometriosis?

Q Chen, T Yang, P Wu, Q Liu, F Wu, H Shi, Z Zhang… - 2024 - intechopen.com
Endometriosis is defined as the ectopic growth of endometrium-like tissue. It brings pain and
infertility to approximately 6–10% of women who are in reproductive age. The pathogenesis …

Genetic-epigenetic aspects of infertility in women with long-COVID-19

OG Boichuk, IS Golovchak… - … Journal «Health of …, 2024 - ujhw.med-expert.com.ua
The aim of the study is to determine the genetic and epigenetic features of infertile patients
with long-term COVID-19 in order to clarify the risk factors for the failure of assisted …