Metal toxicity links to Alzheimer's disease and neuroinflammation
As the median age of the population increases, the number of individuals with Alzheimer's
disease (AD) and the associated socio-economic burden are predicted to worsen. While …
disease (AD) and the associated socio-economic burden are predicted to worsen. While …
Heavy metals exposure and Alzheimer's disease and related dementias
Alzheimer's disease and related dementias lack effective treatment or cures and are major
public health challenges. Risk for Alzheimer's disease and related dementias is partially …
public health challenges. Risk for Alzheimer's disease and related dementias is partially …
Adipose‐derived mesenchymal stem cells reduce autophagy in stroke mice by extracellular vesicle transfer of miR‐25
Y Kuang, X Zheng, L Zhang, X Ai… - Journal of …, 2020 - Wiley Online Library
Grafted mesenchymal stem cells (MSCs) yield neuroprotection in preclinical stroke models
by secreting extracellular vesicles (EVs). The neuroprotective cargo of EVs, however, has …
by secreting extracellular vesicles (EVs). The neuroprotective cargo of EVs, however, has …
Ferroptosis as a mechanism of non-ferrous metal toxicity
Ferroptosis is a recently discovered form of regulated cell death, implicated in multiple
pathologies. Given that the toxicity elicited by some metals is linked to alterations in iron …
pathologies. Given that the toxicity elicited by some metals is linked to alterations in iron …
[HTML][HTML] Manganese-deposited iron oxide promotes tumor-responsive ferroptosis that synergizes the apoptosis of cisplatin
J Cheng, Y Zhu, X **ng, J **ao, H Chen, H Zhang… - Theranostics, 2021 - ncbi.nlm.nih.gov
Background: Ferroptosis is a form of iron-dependent programmed cell death that differs from
apoptosis with regards to both mechanism and cell morphology. Therefore, ferroptotic-based …
apoptosis with regards to both mechanism and cell morphology. Therefore, ferroptotic-based …
Recent advancements of nanomedicine in neurodegenerative disorders theranostics
S Mukherjee, VS Madamsetty… - Advanced Functional …, 2020 - Wiley Online Library
Recent times have witnessed an upsurge in the incidence of neurodegenerative disorders
such as Alzheimer's disease, Parkinson's disease, Huntington's disease, Prion disease, and …
such as Alzheimer's disease, Parkinson's disease, Huntington's disease, Prion disease, and …
Novel upregulation of amyloid-β precursor protein (APP) by microRNA-346 via targeting of APP mRNA 5′-untranslated region: Implications in Alzheimer's disease
In addition to the devastating symptoms of dementia, Alzheimer's disease (AD) is
characterized by accumulation of the processing products of the amyloid-β (Aβ) peptide …
characterized by accumulation of the processing products of the amyloid-β (Aβ) peptide …
The effects of manganese overexposure on brain health
Manganese (Mn) is the twelfth most abundant element on the earth and an essential metal
to human health. Mn is present at low concentrations in a variety of dietary sources, which …
to human health. Mn is present at low concentrations in a variety of dietary sources, which …
Biomarkers of environmental manganese exposure and associations with childhood neurodevelopment: a systematic review and meta-analysis
W Liu, Y **n, Q Li, Y Shang, Z **, J Min… - Environmental …, 2020 - Springer
Background Although prior studies showed a correlation between environmental
manganese (Mn) exposure and neurodevelopmental disorders in children, the results have …
manganese (Mn) exposure and neurodevelopmental disorders in children, the results have …
Manganese-induced neurodegenerative diseases and possible therapeutic approaches
Introduction Neurodegenerative diseases, such as Alzheimer's disease, Parkinson's
disease, Huntington's disease, amyotrophic lateral sclerosis and prion disease represent …
disease, Huntington's disease, amyotrophic lateral sclerosis and prion disease represent …