Tuberculosis still remains one of the most common, communicable, and leading deadliest
diseases known to mankind throughout the world. Drug-resistance in Mycobacterium …

The 1, 4-dihydropyridines (DHPs), a class of drugs, possess a wide variety of biological and
pharmacological actions, have represented one of the most important groups of calcium …

1, 4-Dihydropyridines were introduced in the last century for the treatment of coronary
diseases. Then medicinal chemists decorated the 1, 4-DHP nucleus, the most studied …

Various known and new 3, 4-dihydropyrimidin-2 (1H)-ones and 1, 4-dihydropyridines are
prepared efficiently via Biginelli and Hantzsch reactions using ammonium carbonate in …

During the last two decades, tetrabutylammonium bromide (TBAB) has gained significant
attention as an efficient metal-free homogeneous phase-transfer catalyst. A catalytic amount …

Nowadays, heterocyclic compounds act as a scaffold and are the backbone of medicinal
chemistry. Among all of the heterocyclic scaffolds, 1, 4-Dihydropyridine (1, 4-DHP) is one of …

ABSTRACT The reaction of 2, 6-dimethyl-4-phenyl-1, 4-dihydropyridine-3, 5-
dicarbohydrazide with variety of carbonyl compounds such as substituted benzaldehydes …

The 1, 4-dihydropyridines (DHPs), a class of drugs possess a wide variety of biological and
pharmacological actions. It represents one of the most important groups of calcium-channel …

The pharmacologically privileged DHP derivatives were synthesized using the pragmatic
multicomponent Hantzsch synthesis to screen the antidiabetic activity. Initially, the …

A series of twenty new 4‐substituted‐2, 6‐dimethyl‐3, 5‐bis‐N‐(heteroaryl)‐carbamoyl‐1, 4‐
dihydropyridines have been prepared from a three‐component one‐pot condensation …