Steps in metastasis: an updated review
J Majidpoor, K Mortezaee - Medical Oncology, 2021 - Springer
Metastasis is the most complex and deadly event. Tumor-stromal interface is a place where
invasion of tumor cells in the form of single-cell or collective migration occurs, with the latter …
invasion of tumor cells in the form of single-cell or collective migration occurs, with the latter …
The current knowledge concerning solid cancer and therapy
Solid cancers comprise a large number of new cases and deaths from cancer each year
globally. There are a number of strategies for addressing tumors raised from solid organs …
globally. There are a number of strategies for addressing tumors raised from solid organs …
Targeting fatty acid oxidation to promote anoikis and inhibit ovarian cancer progression
BT Sawyer, L Qamar, TM Yamamoto, A McMellen… - Molecular Cancer …, 2020 - AACR
Epithelial-derived high-grade serous ovarian cancer (HGSOC) is the deadliest gynecologic
malignancy. Roughly 80% of patients are diagnosed with late-stage disease, which is …
malignancy. Roughly 80% of patients are diagnosed with late-stage disease, which is …
CRISPR/Cas: from tumor gene editing to T cell-based immunotherapy of cancer
The clustered regularly interspaced short palindromic repeats system has demonstrated
considerable advantages over other nuclease-based genome editing tools due to its high …
considerable advantages over other nuclease-based genome editing tools due to its high …
Differential effects of the LncRNA RNF157-AS1 on epithelial ovarian cancer cells through suppression of DIRAS3-and ULK1-mediated autophagy
P Xu, S Xu, H Pan, C Dai, Y Xu, L Wang, Y Cong… - Cell death & …, 2023 - nature.com
Analyses of several databases showed that the lncRNA RNF157 Antisense RNA 1 (RNF157-
AS1) is overexpressed in epithelial ovarian cancer (EOC) tissues. In our study, suppressing …
AS1) is overexpressed in epithelial ovarian cancer (EOC) tissues. In our study, suppressing …
CASC4/GOLM2 drives high grade serous carcinoma anoikis resistance through the recycling of EGFR
J Bapat, TM Yamamoto, ER Woodruff, L Qamar… - Cancer Gene …, 2024 - nature.com
Ovarian cancer is the deadliest gynecological malignancy, and accounts for over 150,000
deaths per year worldwide. The high grade serous ovarian carcinoma (HGSC) subtype …
deaths per year worldwide. The high grade serous ovarian carcinoma (HGSC) subtype …
Anoikis in cell fate, physiopathology, and therapeutic interventions
The extracellular matrix (ECM) governs a wide spectrum of cellular fate processes, with a
particular emphasis on anoikis, an integrin‐dependent form of cell death. Currently, anoikis …
particular emphasis on anoikis, an integrin‐dependent form of cell death. Currently, anoikis …
[HTML][HTML] Inhibiting ULK1 kinase decreases autophagy and cell viability in high-grade serous ovarian cancer spheroids
B Singha, J Laski, YR Valdés, E Liu… - American Journal of …, 2020 - ncbi.nlm.nih.gov
Metastasis in high-grade serous ovarian cancer (HGSOC) occurs through an
unconventional route that involves exfoliation of cancer cells from primary tumors and …
unconventional route that involves exfoliation of cancer cells from primary tumors and …
Metabolic profiling of attached and detached metformin and 2-deoxy-D-glucose treated breast cancer cells reveals adaptive changes in metabolome of detached cells
Anchorage-independent growth of cancer cells in vitro is correlated to metastasis formation
in vivo. Metformin use is associated with decreased breast cancer incidence and currently …
in vivo. Metformin use is associated with decreased breast cancer incidence and currently …
Efficient iron utilization compensates for loss of extracellular matrix of ovarian cancer spheroids
Q Wang, T Gu, L Ma, S Bu, W Zhou, G Mao… - Free Radical Biology …, 2021 - Elsevier
Metastasis is the major cause of death in women with advanced ovarian cancer. Epithelial
ovarian cancer cells can dissociate directly from extracellular matrix (ECM) and form …
ovarian cancer cells can dissociate directly from extracellular matrix (ECM) and form …