Recommendations for improving statistical inference in population genomics
The field of population genomics has grown rapidly in response to the recent advent of
affordable, large-scale sequencing technologies. As opposed to the situation during the …
affordable, large-scale sequencing technologies. As opposed to the situation during the …
Challenges in analysis and interpretation of microsatellite data for population genetic studies
Advancing technologies have facilitated the ever‐widening application of genetic markers
such as microsatellites into new systems and research questions in biology. In light of the …
such as microsatellites into new systems and research questions in biology. In light of the …
[HTML][HTML] Clonal dynamics of haematopoiesis across the human lifespan
E Mitchell, M Spencer Chapman, N Williams… - Nature, 2022 - nature.com
Age-related change in human haematopoiesis causes reduced regenerative capacity,
cytopenias, immune dysfunction and increased risk of blood cancer,–, but the reason for …
cytopenias, immune dysfunction and increased risk of blood cancer,–, but the reason for …
De novo assembly, annotation, and comparative analysis of 26 diverse maize genomes
We report de novo genome assemblies, transcriptomes, annotations, and methylomes for
the 26 inbreds that serve as the founders for the maize nested association map** …
the 26 inbreds that serve as the founders for the maize nested association map** …
Efficient ancestry and mutation simulation with msprime 1.0
Stochastic simulation is a key tool in population genetics, since the models involved are
often analytically intractable and simulation is usually the only way of obtaining ground-truth …
often analytically intractable and simulation is usually the only way of obtaining ground-truth …
[KÖNYV][B] Handbook of approximate Bayesian computation
As the world becomes increasingly complex, so do the statistical models required to analyse
the challenging problems ahead. For the very first time in a single volume, the Handbook of …
the challenging problems ahead. For the very first time in a single volume, the Handbook of …
Dynamic changes in genomic and social structures in third millennium BCE central Europe
Europe's prehistory oversaw dynamic and complex interactions of diverse societies, hitherto
unexplored at detailed regional scales. Studying 271 human genomes dated~ 4900 to 1600 …
unexplored at detailed regional scales. Studying 271 human genomes dated~ 4900 to 1600 …
A chromosomal inversion contributes to divergence in multiple traits between deer mouse ecotypes
How locally adapted ecotypes are established and maintained within a species is a long-
standing question in evolutionary biology. Using forest and prairie ecotypes of deer mice …
standing question in evolutionary biology. Using forest and prairie ecotypes of deer mice …
Quantitative evidence for early metastatic seeding in colorectal cancer
Both the timing and molecular determinants of metastasis are unknown, hindering treatment
and prevention efforts. Here we characterize the evolutionary dynamics of this lethal process …
and prevention efforts. Here we characterize the evolutionary dynamics of this lethal process …
Genomic insights into population history and biological adaptation in Oceania
The Pacific region is of major importance for addressing questions regarding human
dispersals, interactions with archaic hominins and natural selection processes. However, the …
dispersals, interactions with archaic hominins and natural selection processes. However, the …