Recommendations for improving statistical inference in population genomics

P Johri, CF Aquadro, M Beaumont, B Charlesworth… - PLoS …, 2022 - journals.plos.org
The field of population genomics has grown rapidly in response to the recent advent of
affordable, large-scale sequencing technologies. As opposed to the situation during the …

Challenges in analysis and interpretation of microsatellite data for population genetic studies

AI Putman, I Carbone - Ecology and evolution, 2014 - Wiley Online Library
Advancing technologies have facilitated the ever‐widening application of genetic markers
such as microsatellites into new systems and research questions in biology. In light of the …

[HTML][HTML] Clonal dynamics of haematopoiesis across the human lifespan

E Mitchell, M Spencer Chapman, N Williams… - Nature, 2022 - nature.com
Age-related change in human haematopoiesis causes reduced regenerative capacity,
cytopenias, immune dysfunction and increased risk of blood cancer,–, but the reason for …

De novo assembly, annotation, and comparative analysis of 26 diverse maize genomes

MB Hufford, AS Seetharam, MR Woodhouse… - Science, 2021 - science.org
We report de novo genome assemblies, transcriptomes, annotations, and methylomes for
the 26 inbreds that serve as the founders for the maize nested association map** …

Efficient ancestry and mutation simulation with msprime 1.0

F Baumdicker, G Bisschop, D Goldstein, G Gower… - Genetics, 2022 - academic.oup.com
Stochastic simulation is a key tool in population genetics, since the models involved are
often analytically intractable and simulation is usually the only way of obtaining ground-truth …

[KÖNYV][B] Handbook of approximate Bayesian computation

SA Sisson, Y Fan, M Beaumont - 2018 - books.google.com
As the world becomes increasingly complex, so do the statistical models required to analyse
the challenging problems ahead. For the very first time in a single volume, the Handbook of …

Dynamic changes in genomic and social structures in third millennium BCE central Europe

L Papac, M Ernée, M Dobeš, M Langová… - Science …, 2021 - science.org
Europe's prehistory oversaw dynamic and complex interactions of diverse societies, hitherto
unexplored at detailed regional scales. Studying 271 human genomes dated~ 4900 to 1600 …

A chromosomal inversion contributes to divergence in multiple traits between deer mouse ecotypes

ER Hager, OS Harringmeyer, TB Wooldridge, S Theingi… - Science, 2022 - science.org
How locally adapted ecotypes are established and maintained within a species is a long-
standing question in evolutionary biology. Using forest and prairie ecotypes of deer mice …

Quantitative evidence for early metastatic seeding in colorectal cancer

Z Hu, J Ding, Z Ma, R Sun, JA Seoane, J Scott Shaffer… - Nature …, 2019 - nature.com
Both the timing and molecular determinants of metastasis are unknown, hindering treatment
and prevention efforts. Here we characterize the evolutionary dynamics of this lethal process …

Genomic insights into population history and biological adaptation in Oceania

J Choin, J Mendoza-Revilla, LR Arauna… - Nature, 2021 - nature.com
The Pacific region is of major importance for addressing questions regarding human
dispersals, interactions with archaic hominins and natural selection processes. However, the …