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Recent progress in the development of fluorescent probes for imaging pathological oxidative stress
Y Geng, Z Wang, J Zhou, M Zhu, J Liu… - Chemical Society …, 2023 - pubs.rsc.org
Oxidative stress is closely related to the physiopathology of numerous diseases. Reactive
oxygen species (ROS), reactive nitrogen species (RNS), and reactive sulfur species (RSS) …
oxygen species (ROS), reactive nitrogen species (RNS), and reactive sulfur species (RSS) …
Stimuli-responsive ferroptosis for cancer therapy
Ferroptosis, an iron-dependent programmed cell death mechanism, is regulated by distinct
molecular pathways of lipid peroxidation caused by intracellular iron supplementation and …
molecular pathways of lipid peroxidation caused by intracellular iron supplementation and …
An Activity‐Based Fluorescent Probe for Imaging Fluctuations of Peroxynitrite (ONOO−) in the Alzheimer's Disease Brain
P Wang, L Yu, J Gong, J **ong, S Zi, H **e… - Angewandte …, 2022 - Wiley Online Library
Peroxynitrite (ONOO−) plays a critical role in Alzheimer's disease (AD). To reveal the
ONOO− influx in AD brains, an activatable activity‐based fluorescence probe Rd‐DPA3 was …
ONOO− influx in AD brains, an activatable activity‐based fluorescence probe Rd‐DPA3 was …
Fluorescent diagnostic probes in neurodegenerative diseases
Neurodegenerative diseases are debilitating disorders that feature progressive and
selective loss of function or structure of anatomically or physiologically associated neuronal …
selective loss of function or structure of anatomically or physiologically associated neuronal …
Pharmacological role of functionalized gold nanoparticles in disease applications
Gold has always been regarded as a symbol of nobility, and its shiny golden appearance
has always attracted the attention of many people. Gold has good ductility, molecular …
has always attracted the attention of many people. Gold has good ductility, molecular …
Near-infrared fluorescence lifetime imaging of amyloid-β aggregates and tau fibrils through the intact skull of mice
Non-invasive methods for the in vivo detection of hallmarks of Alzheimer's disease can
facilitate the study of the progression of the disease in mouse models and may enable its …
facilitate the study of the progression of the disease in mouse models and may enable its …
In Vivo High-resolution Ratiometric Fluorescence Imaging of Inflammation Using NIR-II Nanoprobes with 1550 nm Emission
Quantitatively imaging the spatiotemporal distribution of biological events in living
organisms is essential to understand fundamental biological processes. Self-calibrating …
organisms is essential to understand fundamental biological processes. Self-calibrating …
Simultaneous Sensing of H2S and ATP with a Two-Photon Fluorescent Probe in Alzheimer's Disease: toward Understanding Why H2S Regulates Glutamate …
P Sun, HC Chen, S Lu, J Hai, W Guo, YH **g… - Analytical …, 2022 - ACS Publications
Energy deprivation and reduced levels of hydrogen sulfide (H2S) in the brain is closely
associated with Alzheimer's disease (AD). However, there is currently no fluorescent probe …
associated with Alzheimer's disease (AD). However, there is currently no fluorescent probe …
A general approach to convert hemicyanine dyes into highly optimized photoacoustic scaffolds for analyte sensing
SH Gardner, CJ Brady, C Keeton… - Angewandte Chemie …, 2021 - Wiley Online Library
Most photoacoustic (PA) imaging agents are based on the repurposing of existing
fluorescent dye platforms that exhibit non‐optimal properties for PA applications. Herein, we …
fluorescent dye platforms that exhibit non‐optimal properties for PA applications. Herein, we …
Near-infrared fluorescent probes as imaging and theranostic modalities for amyloid-beta and tau aggregates in Alzheimer's disease
A person suspected of having Alzheimer's disease (AD) is clinically diagnosed for the
presence of principal biomarkers, especially misfolded amyloid-beta (Aβ) and tau proteins in …
presence of principal biomarkers, especially misfolded amyloid-beta (Aβ) and tau proteins in …