Genomics and pathotypes of the many faces of Escherichia coli

J Geurtsen, M de Been, E Weerdenburg… - FEMS microbiology …, 2022 - academic.oup.com
Escherichia coli is the most researched microbial organism in the world. Its varied impact on
human health, consisting of commensalism, gastrointestinal disease, or extraintestinal …

The evolutionary puzzle of Escherichia coli ST131

JDD Pitout, TJ Finn - Infection, Genetics and Evolution, 2020 - Elsevier
The abrupt expansion of Escherichia coli sequence type (ST) 131 is unmatched among
Gram negative bacteria. In many ways, ST131 can be considered a real-world model for the …

Direct antimicrobial resistance prediction from clinical MALDI-TOF mass spectra using machine learning

C Weis, A Cuénod, B Rieck, O Dubuis, S Graf… - Nature Medicine, 2022 - nature.com
Early use of effective antimicrobial treatments is critical for the outcome of infections and the
prevention of treatment resistance. Antimicrobial resistance testing enables the selection of …

Dynamics of extended-spectrum cephalosporin resistance genes in Escherichia coli from Europe and North America

R Zamudio, P Boerlin, R Beyrouthy, JY Madec… - Nature …, 2022 - nature.com
Extended-spectrum cephalosporins (ESCs) are critically important antimicrobial agents for
human and veterinary medicine. ESC resistance (ESC-R) genes have spread worldwide …

An Escherichia coli ST131 pangenome atlas reveals population structure and evolution across 4,071 isolates

AG Decano, T Downing - Scientific reports, 2019 - nature.com
Escherichia coli ST131 is a major cause of infection with extensive antimicrobial resistance
(AMR) facilitated by widespread beta-lactam antibiotic use. This drug pressure has driven …

Genomic comparisons of Escherichia coli ST131 from Australia

D Li, ER Wyrsch, P Elankumaran… - Microbial …, 2021 - microbiologyresearch.org
Escherichia coli ST131 is a globally dispersed extraintestinal pathogenic E. coli lineage
contributing significantly to hospital and community acquired urinary tract and bloodstream …

Phylogroup stability contrasts with high within sequence type complex dynamics of Escherichia coli bloodstream infection isolates over a 12-year period

G Royer, MM Darty, O Clermont, B Condamine… - Genome Medicine, 2021 - Springer
Background Escherichia coli is the leading cause of bloodstream infections, associated with
a significant mortality. Recent genomic analyses revealed that few clonal lineages are …

[HTML][HTML] Dissemination of ESBL-producing E. coli ST131 through wastewater and environmental water in Switzerland

M Biggel, S Hoehn, A Frei, K Dassler, C Jans… - Environmental …, 2023 - Elsevier
The E. coli lineage ST131 is a major cause of multidrug-resistant urinary tract and
bloodstream infections worldwide. Recently emerged ST131 sublineages spread globally …

The role of mobile genetic elements in virulence factor carriage from symptomatic and asymptomatic cases of Escherichia coli bacteriuria

G Morales, B Abelson, S Reasoner, J Miller… - Microbiology …, 2023 - Am Soc Microbiol
Uropathogenic Escherichia coli (UPEC) is extremely diverse genotypically and
phenotypically. Individual strains can variably carry diverse virulence factors, making it …

Epidemiology of ESBL-producing Escherichia coli from repeated prevalence studies over 11 years in a long-term-care facility

R Martischang, P François, A Cherkaoui, N Gaïa… - … Resistance & Infection …, 2021 - Springer
Background Escherichia coli sequence type (ST) 131 H30 is an emerging multidrug
resistant subclone, known to spread and cause outbreaks in long-term care facilities …