Ficus spp.(fig): Ethnobotany and potential as anticancer and anti-inflammatory agents

EP Lansky, HM Paavilainen, AD Pawlus… - Journal of …, 2008 - Elsevier
This review explores medieval, ancient and modern sources for ethnopharmacological uses
of Ficus (fig) species, specifically for employment against malignant disease and …

Natural alkaloids as P-gp inhibitors for multidrug resistance reversal in cancer

P Joshi, RA Vishwakarma, SB Bharate - European journal of medicinal …, 2017 - Elsevier
The biggest challenge associated with cancer chemotherapy is the development of cross
multi-drug resistance to almost all anti-cancer agents upon chronic treatment. The major …

Biologically active indolizidine alkaloids

J Zhang, SL Morris‐Natschke, D Ma… - Medicinal Research …, 2021 - Wiley Online Library
Indolizidine alkaloids are chemical constituents isolated from various marine and terrestrial
plants and animals, including but not limited to trees, fungi, ants, and frogs, with a myriad of …

[HTML][HTML] Applications of Friedel–Crafts reactions in total synthesis of natural products

MM Heravi, V Zadsirjan, P Saedi, T Momeni - RSC advances, 2018 - pubs.rsc.org
Over the years, Friedel–Crafts (FC) reactions have been acknowledged as the most useful
and powerful synthetic tools for the construction of a special kind of carbon–carbon bond …

In Vitro Cytotoxic Activity of Phenanthroindolizidine Alkaloids from Cynanchum vincetoxicum and Tylophora tanakae against Drug-Sensitive and Multidrug …

D Stærk, AK Lykkeberg, J Christensen… - Journal of Natural …, 2002 - ACS Publications
Two known phenanthroindolizidine alkaloids,(−)-(R)-13aα-antofine (1) and (−)-(R)-13aα-6-O-
desmethylantofine (2), and two new natural products,(−)-(R)-13aα-secoantofine (3) and (−) …

Naturally occurring plant isoquinoline N-oxide alkaloids: their pharmacological and SAR activities

VM Dembitsky, TA Gloriozova, VV Poroikov - Phytomedicine, 2015 - Elsevier
The present review describes research on novel natural isoquinoline alkaloids and their N-
oxides isolated from different plant species. More than 200 biological active compounds …

Total syntheses of the Tylophora alkaloids cryptopleurine,(−)‐antofine,(−)‐tylophorine, and (−)‐ficuseptine C

A Fürstner, JWJ Kennedy - Chemistry–A European Journal, 2006 - Wiley Online Library
A concise, efficient and modular approach to the tylophora alkaloids is described, a family of
potent cytotoxic agents that are equally effective against drug sensitive and multidrug …

Phenanthroindolizidines and phenanthroquinolizidines: promising alkaloids for anti-cancer therapy

SR Chemler - Current bioactive compounds, 2009 - ingentaconnect.com
The phenanthroindolizidine and phenanthroquinolizidine alkaloids, typified by tylophorine
and cryptopleurine, are a family of plant-derived small molecules with significant therapeutic …

Preliminary Phytochemical Screening and Antibacterial Properties of Crude Stem Bark Extracts and Fractions of Parkia biglobosa (Jacq.)

EO Abioye, DA Akinpelu, OA Aiyegoro, MF Adegboye… - Molecules, 2013 - mdpi.com
A methanolic crude extract of Parkia biglobosa was prepared and later partitioned in
succession with different solvents of increasing polarity ranging from n-hexane, chloroform …

Biologically active traditional medicinal herbs from Balochistan, Pakistan

MA Zaidi, SA Crow Jr - Journal of ethnopharmacology, 2005 - Elsevier
The biological activities of the following four important medicinal plants of Balochistan,
Pakistan were checked; Grewia erythraea Schwein f.(Tiliaceae), Hymenocrater sessilifolius …