Importance of disrupted intestinal barrier in inflammatory bowel diseases
SY Salim, JD Söderholm - Inflammatory bowel diseases, 2011 - academic.oup.com
The current paradigm of inflammatory bowel diseases (IBD), both Crohn's disease (CD) and
ulcerative colitis (UC), involves the interaction between environmental factors in the …
ulcerative colitis (UC), involves the interaction between environmental factors in the …
Claudins and other tight junction proteins
Epithelial transport relies on the proper function and regulation of the tight junction (TJ),
other‐wise uncontrolled paracellular leakage of solutes and water would occur. They also …
other‐wise uncontrolled paracellular leakage of solutes and water would occur. They also …
Metabolic adaptation to a high-fat diet is associated with a change in the gut microbiota
M Serino, E Luche, S Gres, A Baylac, M Bergé… - Gut, 2012 - gut.bmj.com
Objective The gut microbiota, which is considered a causal factor in metabolic diseases as
shown best in animals, is under the dual influence of the host genome and nutritional …
shown best in animals, is under the dual influence of the host genome and nutritional …
A gut microbial metabolite of linoleic acid, 10-hydroxy-cis-12-octadecenoic acid, ameliorates intestinal epithelial barrier impairment partially via GPR40-MEK-ERK …
J Miyamoto, T Mizukure, SB Park, S Kishino… - Journal of Biological …, 2015 - jbc.org
Gut microbial metabolites of polyunsaturated fatty acids have attracted much attention
because of their various physiological properties. Dysfunction of tight junction (TJ) in the …
because of their various physiological properties. Dysfunction of tight junction (TJ) in the …
Mechanism and consequence of chitosan-mediated reversible epithelial tight junction opening
TH Yeh, LW Hsu, MT Tseng, PL Lee, K Sonjae, YC Ho… - Biomaterials, 2011 - Elsevier
In order to increase the absorption of hydrophilic macromolecules in the small intestine,
permeation enhancers such as chitosan (CS) and its derivatives have been evaluated. The …
permeation enhancers such as chitosan (CS) and its derivatives have been evaluated. The …
Claudins in intestines: Distribution and functional significance in health and diseases
Z Lu, L Ding, Q Lu, YH Chen - Tissue barriers, 2013 - Taylor & Francis
Intestines are organs that not only digest food and absorb nutrients, but also provide a
defense barrier against pathogens and noxious agents ingested. Tight junctions (TJs) are …
defense barrier against pathogens and noxious agents ingested. Tight junctions (TJs) are …
The interplay between herbal medicines and gut microbiota in metabolic diseases
L Wang, X Gou, Y Ding, J Liu, Y Wang… - Frontiers in …, 2023 - frontiersin.org
Globally, metabolic diseases are becoming a major public health problem. Herbal
medicines are medicinal materials or preparations derived from plants and are widely used …
medicines are medicinal materials or preparations derived from plants and are widely used …
Baizhu shaoyao decoction restores the intestinal barrier and brain–gut axis balance to alleviate diarrhea-predominant irritable bowel syndrome via FoxO1/FoxO3a
Y Wei, Y Fan, S Huang, J Lv, Y Zhang, Z Hao - Phytomedicine, 2024 - Elsevier
Background Diarrhea-predominant irritable bowel syndrome (IBS-D) is a common functional
gastrointestinal disease. Besides, baizhu shaoyao decoction (BSD) is an effective treatment …
gastrointestinal disease. Besides, baizhu shaoyao decoction (BSD) is an effective treatment …
Molecular modulation of intestinal epithelial barrier: contribution of microbiota
The daunting task required of the gut‐barrier to prevent luminal pathogens and harmful
substances from entering into the internal milieu and yet promoting digestion and absorption …
substances from entering into the internal milieu and yet promoting digestion and absorption …
Direct and indirect effects of pathogenic bacteria on the integrity of intestinal barrier
LZ Shu, YD Ding, QM Xue, W Cai… - Therapeutic Advances …, 2023 - journals.sagepub.com
Bacterial translocation is a pathological process involving migration of pathogenic bacteria
across the intestinal barrier to enter the systemic circulation and gain access to distant …
across the intestinal barrier to enter the systemic circulation and gain access to distant …