Intracellular transport driven by cytoskeletal motors: General mechanisms and defects

C Appert-Rolland, M Ebbinghaus, L Santen - Physics Reports, 2015 - Elsevier
Cells are the elementary units of living organisms, which are able to carry out many vital
functions. These functions rely on active processes on a microscopic scale. Therefore, they …

Causes, costs and consequences of kinesin motors communicating through the microtubule lattice

KJ Verhey, R Ohi - Journal of Cell Science, 2023 - journals.biologists.com
Microtubules are critical for a variety of important functions in eukaryotic cells. During
intracellular trafficking, molecular motor proteins of the kinesin superfamily drive the …

Kinesin-binding–triggered conformation switching of microtubules contributes to polarized transport

T Shima, M Morikawa, J Kaneshiro, T Kambara… - Journal of Cell …, 2018 - rupress.org
Kinesin-1, the founding member of the kinesin superfamily of proteins, is known to use only
a subset of microtubules for transport in living cells. This biased use of microtubules is …

[КНИГА][B] Out-of-equilibrium (supra) molecular systems and materials

N Giuseppone, A Walther - 2021 - books.google.com
Out-of-Equilibrium (Supra) molecular Systems and Materials A must-have resource that
covers everything from out-of-equilibrium chemical systems to active materials Out-of …

Processive movement of single kinesins on crowded microtubules visualized using quantum dots

A Seitz, T Surrey - The EMBO journal, 2006 - embopress.org
Kinesin‐1 is a processive molecular motor transporting cargo along microtubules. Inside
cells, several motors and microtubule‐associated proteins compete for binding to …

Protein displacement by an assembly of helicase molecules aligned along single-stranded DNA

AK Byrd, KD Raney - Nature structural & molecular biology, 2004 - nature.com
Helicases are molecular motors that unwind double-stranded DNA or RNA. In addition to
unwinding nucleic acids, an important function of these enzymes seems to be the disruption …

Motor guidance by long-range communication on the microtubule highway

SS Wijeratne, SA Fiorenza, AE Neary… - Proceedings of the …, 2022 - pnas.org
Coupling of motor proteins within arrays drives muscle contraction, flagellar beating,
chromosome segregation, and other biological processes. Current models of motor coupling …

Microscopic interactions control a structural transition in active mixtures of microtubules and molecular motors

B Najma, WS Wei, A Baskaran, PJ Foster… - Proceedings of the …, 2024 - pnas.org
Microtubules and molecular motors are essential components of the cellular cytoskeleton,
driving fundamental processes in vivo, including chromosome segregation and cargo …

Modulation of kinesin's load-bearing capacity by force geometry and the microtubule track

S Pyrpassopoulos, H Shuman, EM Ostap - Biophysical journal, 2020 - cell.com
Kinesin motors and their associated microtubule tracks are essential for long-distance
transport of cellular cargos. Intracellular activity and proper recruitment of kinesins is …

Microtubule length regulation by molecular motors

A Melbinger, L Reese, E Frey - Physical review letters, 2012 - APS
Length regulation of microtubules (MTs) is essential for many cellular processes. Molecular
motors like kinesin-8, which move along MTs and also act as depolymerases, are known as …