Intracellular transport driven by cytoskeletal motors: General mechanisms and defects
C Appert-Rolland, M Ebbinghaus, L Santen - Physics Reports, 2015 - Elsevier
Cells are the elementary units of living organisms, which are able to carry out many vital
functions. These functions rely on active processes on a microscopic scale. Therefore, they …
functions. These functions rely on active processes on a microscopic scale. Therefore, they …
Causes, costs and consequences of kinesin motors communicating through the microtubule lattice
Microtubules are critical for a variety of important functions in eukaryotic cells. During
intracellular trafficking, molecular motor proteins of the kinesin superfamily drive the …
intracellular trafficking, molecular motor proteins of the kinesin superfamily drive the …
Kinesin-binding–triggered conformation switching of microtubules contributes to polarized transport
T Shima, M Morikawa, J Kaneshiro, T Kambara… - Journal of Cell …, 2018 - rupress.org
Kinesin-1, the founding member of the kinesin superfamily of proteins, is known to use only
a subset of microtubules for transport in living cells. This biased use of microtubules is …
a subset of microtubules for transport in living cells. This biased use of microtubules is …
Processive movement of single kinesins on crowded microtubules visualized using quantum dots
A Seitz, T Surrey - The EMBO journal, 2006 - embopress.org
Kinesin‐1 is a processive molecular motor transporting cargo along microtubules. Inside
cells, several motors and microtubule‐associated proteins compete for binding to …
cells, several motors and microtubule‐associated proteins compete for binding to …
Protein displacement by an assembly of helicase molecules aligned along single-stranded DNA
Helicases are molecular motors that unwind double-stranded DNA or RNA. In addition to
unwinding nucleic acids, an important function of these enzymes seems to be the disruption …
unwinding nucleic acids, an important function of these enzymes seems to be the disruption …
Motor guidance by long-range communication on the microtubule highway
SS Wijeratne, SA Fiorenza, AE Neary… - Proceedings of the …, 2022 - National Acad Sciences
Coupling of motor proteins within arrays drives muscle contraction, flagellar beating,
chromosome segregation, and other biological processes. Current models of motor coupling …
chromosome segregation, and other biological processes. Current models of motor coupling …
Modulation of kinesin's load-bearing capacity by force geometry and the microtubule track
S Pyrpassopoulos, H Shuman, EM Ostap - Biophysical journal, 2020 - cell.com
Kinesin motors and their associated microtubule tracks are essential for long-distance
transport of cellular cargos. Intracellular activity and proper recruitment of kinesins is …
transport of cellular cargos. Intracellular activity and proper recruitment of kinesins is …
Microtubule length regulation by molecular motors
Length regulation of microtubules (MTs) is essential for many cellular processes. Molecular
motors like kinesin-8, which move along MTs and also act as depolymerases, are known as …
motors like kinesin-8, which move along MTs and also act as depolymerases, are known as …
Single-molecule imaging and kinetic analysis of cooperative cofilin–actin filament interactions
K Hayakawa, S Sakakibara… - Proceedings of the …, 2014 - National Acad Sciences
The actin filament-severing protein actin depolymerizing factor (ADF)/cofilin is ubiquitously
distributed among eukaryotes and modulates actin dynamics. The cooperative binding of …
distributed among eukaryotes and modulates actin dynamics. The cooperative binding of …
Modelling microtubule patterns
E Karsenti, F Nédélec, T Surrey - Nature cell biology, 2006 - nature.com
The cellular cytoskeleton is well studied in terms of its biological and physical properties,
making it an attractive subject for systems approaches. Here, we describe the experimental …
making it an attractive subject for systems approaches. Here, we describe the experimental …