Renal cell carcinoma (RCC) is the most common type of urogenital cancer. It has a mortality
rate of 30-40% and is more commonly seen in men than women. In addition to gender, other …

Renal cell carcinoma (RCC) is the most common type of kidney cancer and comprises
several subtypes with unique characteristics. The most common subtype (~ 70% of cases) is …

Abstract The Genitourinary Pathology Society (GUPS) reviewed recent advances in renal
neoplasia, particularly post-2016 World Health Organization (WHO) classification, to provide …

Abstract The Cancer Genome Atlas (TCGA) characterized the somatic genetic and genomic
alterations in renal cell carcinoma (RCC) encompassing the major RCC histological …

Mutational signature analysis is commonly performed in cancer genomic studies. Here, we
present SigProfilerExtractor, an automated tool for de novo extraction of mutational …

Attempts to develop MET-targeted therapies have historically focused on MET-expressing
cancers, with limited success. Thus, MET expression in the absence of a genomic marker of …

Purpose: This AUA Guideline focuses on evaluation/counseling and management of adult
patients with clinically localized renal masses suspicious for cancer, including solid …

The MiT‐TFE family of basic helix‐loop‐helix leucine‐zipper transcription factors includes
four members: TFEB, TFE 3, TFEC, and MITF. Originally described as oncogenes, these …

Copper is an essential nutrient for maintaining enzyme activity and transcription factor
function. Excess copper results in the aggregation of lipoylated dihydrolipoamide S …

Abstract We analyzed transcriptomes (n= 211), whole exomes (n= 99) and targeted exomes
(n= 103) from 216 malignant pleural mesothelioma (MPM) tumors. Using RNA-seq data, we …