Secondary structural ensembles of the SARS-CoV-2 RNA genome in infected cells
SARS-CoV-2 is a betacoronavirus with a single-stranded, positive-sense, 30-kilobase RNA
genome responsible for the ongoing COVID-19 pandemic. Although population average …
genome responsible for the ongoing COVID-19 pandemic. Although population average …
SARS-CoV-2 expresses a microRNA-like small RNA able to selectively repress host genes
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of
coronavirus disease (COVID-19), continues to be a pressing health concern. In this study …
coronavirus disease (COVID-19), continues to be a pressing health concern. In this study …
Structural and functional RNA motifs of SARS-CoV-2 and Influenza A virus as a target of viral inhibitors
I Szczesniak, A Baliga-Gil, A Jarmolowicz… - International Journal of …, 2023 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the
COVID-19 pandemic, whereas the influenza A virus (IAV) causes seasonal epidemics and …
COVID-19 pandemic, whereas the influenza A virus (IAV) causes seasonal epidemics and …
Biomotors, viral assembly, and RNA nanobiotechnology: Current achievements and future directions
Abstract The International Society of RNA Nanotechnology and Nanomedicine (ISRNN)
serves to further the development of a wide variety of functional nucleic acids and other …
serves to further the development of a wide variety of functional nucleic acids and other …
Targeting genomic SARS-CoV-2 RNA with siRNAs allows efficient inhibition of viral replication and spread
A promising approach to tackle the severe acute respiratory syndrome coronavirus-2 (SARS-
CoV-2) could be small interfering (si) RNAs. So far it is unclear, which viral replication steps …
CoV-2) could be small interfering (si) RNAs. So far it is unclear, which viral replication steps …
Comprehensive map** of SARS-CoV-2 interactions in vivo reveals functional virus-host interactions
SARS-CoV-2 is a major threat to global health. Here, we investigate the RNA structure and
RNA-RNA interactions of wildtype (WT) and a mutant (Δ382) SARS-CoV-2 in cells using …
RNA-RNA interactions of wildtype (WT) and a mutant (Δ382) SARS-CoV-2 in cells using …
To knot or not to knot: multiple conformations of the SARS-CoV-2 frameshifting RNA element
The SARS-CoV-2 frameshifting RNA element (FSE) is an excellent target for therapeutic
intervention against Covid-19. This small gene element employs a shifting mechanism to …
intervention against Covid-19. This small gene element employs a shifting mechanism to …
Length-dependent motions of SARS-CoV-2 frameshifting RNA pseudoknot and alternative conformations suggest avenues for frameshifting suppression
The SARS-CoV-2 frameshifting element (FSE), a highly conserved mRNA region required
for correct translation of viral polyproteins, defines an excellent therapeutic target against …
for correct translation of viral polyproteins, defines an excellent therapeutic target against …
A viral pan-end RNA element and host complex define a SARS-CoV-2 regulon
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of
COVID-19, generates multiple protein-coding, subgenomic RNAs (sgRNAs) from a longer …
COVID-19, generates multiple protein-coding, subgenomic RNAs (sgRNAs) from a longer …
Regulation of coronavirus nsp15 cleavage specificity by RNA structure
SARS-CoV-2, the etiologic agent of the COVID-19 pandemic, has had an enduring impact
on global public health. However, SARS-CoV-2 is only one of multiple pathogenic human …
on global public health. However, SARS-CoV-2 is only one of multiple pathogenic human …