The landscape of cancer research and cancer care in China
Z Lu, Y Chen, D Liu, X Jiao, C Liu, Y Wang, Z Zhang… - Nature Medicine, 2023 - nature.com
The rising cancer incidence rate in China poses a substantial public health concern,
although there have been remarkable improvements in the country's cancer mortality and …
although there have been remarkable improvements in the country's cancer mortality and …
Application of artificial intelligence for improving early detection and prediction of therapeutic outcomes for gastric cancer in the era of precision oncology
Z Wang, Y Liu, X Niu - Seminars in Cancer Biology, 2023 - Elsevier
Gastric cancer is a leading contributor to cancer incidence and mortality globally. Recently,
artificial intelligence approaches, particularly machine learning and deep learning, are …
artificial intelligence approaches, particularly machine learning and deep learning, are …
Neoadjuvant atezolizumab plus chemotherapy in gastric and gastroesophageal junction adenocarcinoma: the phase 2 PANDA trial
YL Verschoor, J van de Haar, JG van den Berg… - Nature medicine, 2024 - nature.com
Gastric and gastroesophageal junction (G/GEJ) cancers carry a poor prognosis, and despite
recent advancements, most patients die of their disease. Although immune checkpoint …
recent advancements, most patients die of their disease. Although immune checkpoint …
Multiplex immunofluorescence and single‐cell transcriptomic profiling reveal the spatial cell interaction networks in the non‐small cell lung cancer microenvironment
H Peng, X Wu, S Liu, M He, C **e… - Clinical and …, 2023 - Wiley Online Library
Background Conventional immunohistochemistry technologies were limited by the inability
to simultaneously detect multiple markers and the lack of identifying spatial relationships …
to simultaneously detect multiple markers and the lack of identifying spatial relationships …
Neutrophil profiling illuminates anti-tumor antigen-presenting potency
Y Wu, J Ma, X Yang, F Nan, T Zhang, S Ji, D Rao… - Cell, 2024 - cell.com
Neutrophils, the most abundant and efficient defenders against pathogens, exert opposing
functions across cancer types. However, given their short half-life, it remains challenging to …
functions across cancer types. However, given their short half-life, it remains challenging to …
Predicting gastric cancer response to anti-HER2 therapy or anti-HER2 combined immunotherapy based on multi-modal data
The sole use of single modality data often fails to capture the complex heterogeneity among
patients, including the variability in resistance to anti-HER2 therapy and outcomes of …
patients, including the variability in resistance to anti-HER2 therapy and outcomes of …
[HTML][HTML] Artificial intelligence for predictive biomarker discovery in immuno-oncology: a systematic review
Background The widespread use of Immune checkpoint-inhibitors (ICI) has revolutionised
treatment of multiple cancer types. However, selecting patients who may benefit from ICI …
treatment of multiple cancer types. However, selecting patients who may benefit from ICI …
CLDN18. 2 expression and its impact on prognosis and the immune microenvironment in gastric cancer
C Wang, Y Wang, J Chen, Y Wang, C Pang… - BMC …, 2023 - Springer
Background The investigational use of zolbetuximab (IMAB362), a groundbreaking
monoclonal antibody medication targeting claudin 18.2 (CLDN18. 2), for treatment of …
monoclonal antibody medication targeting claudin 18.2 (CLDN18. 2), for treatment of …
Multiplex protein imaging in tumour biology
Tissue imaging has become much more colourful in the past decade. Advances in both
experimental and analytical methods now make it possible to image protein markers in …
experimental and analytical methods now make it possible to image protein markers in …
Predictive biomarkers for immunotherapy in gastric cancer: current status and emerging prospects
W Hou, Y Zhao, H Zhu - International Journal of Molecular Sciences, 2023 - mdpi.com
Gastric cancer presents substantial management challenges, and the advent of
immunotherapy has ignited renewed hope among patients. Nevertheless, a significant …
immunotherapy has ignited renewed hope among patients. Nevertheless, a significant …