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[HTML][HTML] Oral delivery of therapeutic peptides and proteins: Technology landscape of lipid-based nanocarriers
The oral administration of therapeutic peptides and proteins is favoured from a patient and
commercial point of view. In order to reach the systemic circulation after oral administration …
commercial point of view. In order to reach the systemic circulation after oral administration …
Personalized cancer nanomedicine: overcoming biological barriers for intracellular delivery of biopharmaceuticals
The success of personalized medicine in oncology relies on using highly effective and
precise therapeutic modalities such as small interfering RNA (siRNA) and monoclonal …
precise therapeutic modalities such as small interfering RNA (siRNA) and monoclonal …
Translational aspect in peptide drug discovery and development: An emerging therapeutic candidate
U Anand, A Bandyopadhyay, NK Jha… - Biofactors, 2023 - Wiley Online Library
In the last two decades, protein–protein interactions (PPIs) have been used as the main
target for drug development. However, with larger or superficial binding sites, it has been …
target for drug development. However, with larger or superficial binding sites, it has been …
Lipid nanoparticles as promising carriers for mRNA vaccines for viral lung infections
M Hajiaghapour Asr, F Dayani, F Saedi Segherloo… - Pharmaceutics, 2023 - mdpi.com
In recent years, there has been an increase in deaths due to infectious diseases, most
notably in the context of viral respiratory pathogens. Consequently, the focus has shifted in …
notably in the context of viral respiratory pathogens. Consequently, the focus has shifted in …
Pectin-based nanoencapsulation strategy to improve the bioavailability of bioactive compounds
Pectin is one of the polysaccharides to be used as a coating nanomaterial. The
characteristics of pectin are suitable to form nanostructures for protection, increased …
characteristics of pectin are suitable to form nanostructures for protection, increased …
Cell-penetrating peptides for transmucosal delivery of proteins
Enabling non-invasive delivery of proteins across the mucosal barriers promises improved
patient compliance and therapeutic efficacies. Cell-penetrating peptides (CPPs) are …
patient compliance and therapeutic efficacies. Cell-penetrating peptides (CPPs) are …
Antithrombotic therapy by regulating the ROS‐mediated thrombosis microenvironment and specific nonpharmaceutical thrombolysis using prussian blue nanodroplets
W Zhang, J Wang, Z **e, H Zou, Q Chen, L Xu, L Hu… - Small, 2022 - Wiley Online Library
In thrombotic diseases, the effects of reactive oxygen species (ROS)‐mediated oxidative
stress as a “perpetrator” in thrombosis must be resolved. Accordingly, an insufficient …
stress as a “perpetrator” in thrombosis must be resolved. Accordingly, an insufficient …
Nanoplatform based intranasal vaccines: current progress and clinical challenges
Z Bai, D Wan, T Lan, W Hong, H Dong, Y Wei, X Wei - ACS nano, 2024 - ACS Publications
Multiple vaccine platforms have been employed to develop the nasal SARS-CoV-2 vaccines
in preclinical studies, and the dominating pipelines are viral vectored as protein-based …
in preclinical studies, and the dominating pipelines are viral vectored as protein-based …
Emerging strategies for nanomedicine in autoimmunity
Autoimmune disorders have risen to be among the most prevalent chronic diseases across
the globe, affecting approximately 5–7% of the population. As autoimmune diseases steadily …
the globe, affecting approximately 5–7% of the population. As autoimmune diseases steadily …
Approved delivery strategies for biopharmaceuticals
In recent years, biopharmaceuticals have witnessed remarkable advancements,
transforming the landscape of therapeutic interventions. Biopharmaceuticals encompassing …
transforming the landscape of therapeutic interventions. Biopharmaceuticals encompassing …