Biomechanical factors in osteoarthritis
F Guilak - Best practice & research Clinical rheumatology, 2011 - Elsevier
Biomechanical factors play an important role in the health of diarthrodial joints. Altered joint
loading–associated to obesity, malalignment, trauma or joint instability–is a critical risk factor …
loading–associated to obesity, malalignment, trauma or joint instability–is a critical risk factor …
Na+, K+-ATPase isozyme diversity; comparative biochemistry and physiological implications of novel functional interactions
Na+, K+-ATPase is ubiquitously expressed in the plasma membrane ofall animal cells
where it serves as the principal regulator of intracellularion homeostasis. Na+, K+-ATPase is …
where it serves as the principal regulator of intracellularion homeostasis. Na+, K+-ATPase is …
Regulation of chondrogenesis and chondrocyte differentiation by stress
Chondrogenesis and endochondral ossification are the cartilage differentiation processes
that lead to skeletal formation and growth in the develo** vertebrate as well as skeletal …
that lead to skeletal formation and growth in the develo** vertebrate as well as skeletal …
Mesenchymal stem cells in regenerative medicine: opportunities and challenges for articular cartilage and intervertebral disc tissue engineering
SM Richardson, JA Hoyland… - Journal of cellular …, 2010 - Wiley Online Library
Defects of load‐bearing connective tissues such as articular cartilage and intervertebral disc
(IVD) can result from trauma, degenerative, endocrine, or age‐related disease. Current …
(IVD) can result from trauma, degenerative, endocrine, or age‐related disease. Current …
The effects of osmotic stress on the viscoelastic and physical properties of articular chondrocytes
F Guilak, GR Erickson, HP Ting-Beall - Biophysical journal, 2002 - cell.com
The metabolic activity of chondrocytes in articular cartilage is influenced by alterations in the
osmotic environment of the tissue, which occur secondary to mechanical compression. The …
osmotic environment of the tissue, which occur secondary to mechanical compression. The …
Integrins and stretch activated ion channels; putative components of functional cell surface mechanoreceptors in articular chondrocytes
Perception of mechanical signals and the biological responses to such stimuli are
fundamental properties of load bearing articular cartilage in diarthrodial joints. Chondrocytes …
fundamental properties of load bearing articular cartilage in diarthrodial joints. Chondrocytes …
Perlecan in pericellular mechanosensory cell-matrix communication, extracellular matrix stabilisation and mechanoregulation of load-bearing connective tissues
In this study, we review mechanoregulatory roles for perlecan in load-bearing connective
tissues. Perlecan facilitates the co-acervation of tropoelastin and assembly of elastic …
tissues. Perlecan facilitates the co-acervation of tropoelastin and assembly of elastic …
[HTML][HTML] The chondrocyte channelome: A narrative review
Chondrocytes are the main cells in the extracellular matrix (ECM) of articular cartilage and
possess a highly differentiated phenotype that is the hallmark of the unique physiological …
possess a highly differentiated phenotype that is the hallmark of the unique physiological …
The deformation behavior and viscoelastic properties of chondrocytes in articular cartilage
F Guilak - Biorheology, 2000 - content.iospress.com
Chondrocytes in articular cartilage utilize mechanical signals in conjunction with other
environmental factors to regulate their metabolic activity. However, the sequence of …
environmental factors to regulate their metabolic activity. However, the sequence of …
Sodium sensing in the interstitium and relationship to hypertension
J Titze, A Machnik - Current opinion in nephrology and …, 2010 - journals.lww.com
Sodium sensing in the interstitium and relationship to hyper... : Current Opinion in Nephrology
and Hypertension Sodium sensing in the interstitium and relationship to hypertension : Current …
and Hypertension Sodium sensing in the interstitium and relationship to hypertension : Current …