This review considers the most recent developments in supramolecular and supraparticle
structures obtained from natural, renewable biopolymers as well as their disassembly and …

Antimicrobial resistance is one of the major problems in current practical medicine. The
spread of genes coding for resistance determinants among bacteria challenges the use of …

Biomolecular condensates play a key role in organizing cellular fluids such as the cytoplasm
and nucleoplasm. Most of these non-membranous organelles show liquid-like properties …

In-cell structural biology aims at extracting structural information about proteins or nucleic
acids in their native, cellular environment. This emerging field holds great promise and is …

The complexity of nanoscale interactions between biomaterials and cells has limited the
realization of the ultimate vision of nanotechnology in diagnostics and therapeutics. As such …

Constructing a minimal machinery for autonomous self-division of synthetic cells is a major
goal of bottom-up synthetic biology. One paradigm has been the E. coli divisome, with the …

The molecular machinery that enables life has evolved in water, yet many of the organisms
around us are able to survive even extreme desiccation. Especially remarkable are single …

Single-cell RNA sequencing (scRNA-seq) has emerged as a central genome-wide method
to characterize cellular identities and processes. Consequently, improving its sensitivity …

One of the grand challenges of biophysical chemistry is to understand the principles that
govern protein misfolding and aggregation, which is a highly complex process that is …

Macromolecular crowding affects the activity of proteins and functional macromolecular
complexes in all cells, including bacteria. Crowding, together with physicochemical …