The extended granin family: structure, function, and biomedical implications
The chromogranins (chromogranin A and chromogranin B), secretogranins (secretogranin II
and secretogranin III), and additional related proteins (7B2, NESP55, proSAAS, and VGF) …
and secretogranin III), and additional related proteins (7B2, NESP55, proSAAS, and VGF) …
VGF as a biomarker and therapeutic target in neurodegenerative and psychiatric diseases
JP Quinn, SE Kandigian, BA Trombetta… - Brain …, 2021 - academic.oup.com
Neurosecretory protein VGF (non-acronymic) belongs to the granin family of neuropeptides.
VGF and VGF-derived peptides have been repeatedly identified in well-powered and well …
VGF and VGF-derived peptides have been repeatedly identified in well-powered and well …
Multiscale causal networks identify VGF as a key regulator of Alzheimer's disease
Though discovered over 100 years ago, the molecular foundation of sporadic Alzheimer's
disease (AD) remains elusive. To better characterize the complex nature of AD, we …
disease (AD) remains elusive. To better characterize the complex nature of AD, we …
Multifaceted effects of oligodendroglial exosomes on neurons: impact on neuronal firing rate, signal transduction and gene regulation
D Fröhlich, WP Kuo, C Frühbeis… - … of the Royal …, 2014 - royalsocietypublishing.org
Exosomes are small membranous vesicles of endocytic origin that are released by almost
every cell type. They exert versatile functions in intercellular communication important for …
every cell type. They exert versatile functions in intercellular communication important for …
Large-scale proteomic analysis of human brain identifies proteins associated with cognitive trajectory in advanced age
In advanced age, some individuals maintain a stable cognitive trajectory while others
experience a rapid decline. Such variation in cognitive trajectory is only partially explained …
experience a rapid decline. Such variation in cognitive trajectory is only partially explained …
[ΒΙΒΛΙΟ][B] Exercise psychology
J Buckworth - 2013 - books.google.com
Exercise Psychology, Second Edition, addresses the psychological and biological
consequences of exercise and physical activity and their subsequent effects on mood and …
consequences of exercise and physical activity and their subsequent effects on mood and …
Haploinsufficiency of the autism-associated Shank3 gene leads to deficits in synaptic function, social interaction, and social communication
O Bozdagi, T Sakurai, D Papapetrou, X Wang… - Molecular autism, 2010 - Springer
Background SHANK3 is a protein in the core of the postsynaptic density (PSD) and has a
critical role in recruiting many key functional elements to the PSD and to the synapse …
critical role in recruiting many key functional elements to the PSD and to the synapse …
Synaptic proteins in CSF as potential novel biomarkers for prognosis in prodromal Alzheimer's disease
Background We investigated whether a panel of 12 potential novel biomarkers consisting of
proteins involved in synapse functioning and immunity would be able to distinguish patients …
proteins involved in synapse functioning and immunity would be able to distinguish patients …
Identification and validation of novel cerebrospinal fluid biomarkers for staging early Alzheimer's disease
RJ Perrin, R Craig-Schapiro, JP Malone, AR Shah… - PloS one, 2011 - journals.plos.org
Background Ideally, disease modifying therapies for Alzheimer disease (AD) will be applied
during the 'preclinical'stage (pathology present with cognition intact) before severe neuronal …
during the 'preclinical'stage (pathology present with cognition intact) before severe neuronal …
Two divergent leptin paralogues in zebrafish (Danio rerio) that originate early in teleostean evolution
The production of peptide hormones by skeletal muscle tissue is a promising area of gene
therapy. Skeletal muscle myogenesis can be induced in vitro, resulting in the fusion of …
therapy. Skeletal muscle myogenesis can be induced in vitro, resulting in the fusion of …