Extensive research over the past half a century indicates that reactive oxygen species (ROS)
play an important role in cancer. Although low levels of ROS can be beneficial, excessive …

Simple Summary Colorectal cancer (CRC) is very common throughout the world. Despite an
improved outcome with the current treatment regimen, a huge number of patients relapse …

Significance: Extensive research during the last quarter century has revealed that reactive
oxygen species (ROS) produced in the body, primarily by the mitochondria, play a major role …

Breast cancer is one of the most common cancers worldwide with a rising incidence, and is
the leading cause of cancer-related death among females. Angiogenesis plays an important …

Inflammation is an essential immune response characterized by pain, swelling, redness,
heat, and impaired function. A controlled acute inflammatory response is necessary to fight …

MicroRNAs play an important regulatory role in carcinogenesis and cancer metastasis.
Different members of let-7 family have been reported to be decreased in human lung tumors …

Tumor metastasis is a hallmark of colorectal cancer (CRC), in which exosome plays a crucial
role with its function in intercellular communication. Plasma exosomes were collected from …

Redox imbalance is resulted from the destruction of balance between oxidants and
antioxidants. The dominant oxidants are reactive oxygen species (ROS), which are involved …

β3 integrin (ITGB3), also known as CD61 or GP3A, is one of the most widely studied
components in the integrin family. As an adhesion receptor on the cell surface, ITGB3 …

Colorectal cancer (CRC), one of the most common human malignancies, is a major public
health problem in the developed world. Capsaicin, widely used as a food additive and as an …