Candidate biomarkers in psychiatric disorders: state of the field

A Abi‐Dargham, SJ Moeller, F Ali… - World …, 2023 - Wiley Online Library
The field of psychiatry is hampered by a lack of robust, reliable and valid biomarkers that can
aid in objectively diagnosing patients and providing individualized treatment …

[HTML][HTML] The human connectome project: a retrospective

JS Elam, MF Glasser, MP Harms, SN Sotiropoulos… - NeuroImage, 2021 - Elsevier
Abstract The Human Connectome Project (HCP) was launched in 2010 as an ambitious
effort to accelerate advances in human neuroimaging, particularly for measures of brain …

A somato-cognitive action network alternates with effector regions in motor cortex

EM Gordon, RJ Chauvin, AN Van, A Rajesh, A Nielsen… - Nature, 2023 - nature.com
Motor cortex (M1) has been thought to form a continuous somatotopic homunculus
extending down the precentral gyrus from foot to face representations,, despite evidence for …

Psilocybin desynchronizes the human brain

JS Siegel, S Subramanian, D Perry, BP Kay… - Nature, 2024 - nature.com
A single dose of psilocybin, a psychedelic that acutely causes distortions of space–time
perception and ego dissolution, produces rapid and persistent therapeutic effects in human …

Reproducible brain-wide association studies require thousands of individuals

S Marek, B Tervo-Clemmens, FJ Calabro, DF Montez… - Nature, 2022 - nature.com
Magnetic resonance imaging (MRI) has transformed our understanding of the human brain
through well-replicated map** of abilities to specific structures (for example, lesion …

Frontostriatal salience network expansion in individuals in depression

CJ Lynch, IG Elbau, T Ng, A Ayaz, S Zhu, D Wolk… - Nature, 2024 - nature.com
Decades of neuroimaging studies have shown modest differences in brain structure and
connectivity in depression, hindering mechanistic insights or the identification of risk factors …

Data leakage inflates prediction performance in connectome-based machine learning models

M Rosenblatt, L Tejavibulya, R Jiang, S Noble… - Nature …, 2024 - nature.com
Predictive modeling is a central technique in neuroimaging to identify brain-behavior
relationships and test their generalizability to unseen data. However, data leakage …

A precision functional atlas of personalized network topography and probabilities

RJM Hermosillo, LA Moore, E Feczko… - Nature …, 2024 - nature.com
Although the general location of functional neural networks is similar across individuals,
there is vast person-to-person topographic variability. To capture this, we implemented …

[HTML][HTML] Brain charts for the human lifespan

RAI Bethlehem, J Seidlitz, SR White, JW Vogel… - Nature, 2022 - nature.com
Over the past few decades, neuroimaging has become a ubiquitous tool in basic research
and clinical studies of the human brain. However, no reference standards currently exist to …

The OpenNeuro resource for sharing of neuroscience data

CJ Markiewicz, KJ Gorgolewski, F Feingold, R Blair… - Elife, 2021 - elifesciences.org
The sharing of research data is essential to ensure reproducibility and maximize the impact
of public investments in scientific research. Here, we describe OpenNeuro, a BRAIN …