Coiled‐coils: The long and short of it

L Truebestein, TA Leonard - Bioessays, 2016 - Wiley Online Library
Coiled‐coils are found in proteins throughout all three kingdoms of life. Coiled‐coil domains
of some proteins are almost invariant in sequence and length, betraying a structural and …

Coiled coils–a model system for the 21st century

AN Lupas, J Bassler - Trends in biochemical sciences, 2017 - cell.com
α-Helical coiled coils were described more than 60 years ago as simple, repetitive structures
mediating oligomerization and mechanical stability. Over the past 20 years, however, they …

A multidomain connector links the outer membrane and cell wall in phylogenetically deep-branching bacteria

A von Kügelgen, S van Dorst, V Alva… - Proceedings of the …, 2022 - National Acad Sciences
Deinococcus radiodurans is a phylogenetically deep-branching extremophilic bacterium that
is remarkably tolerant to numerous environmental stresses, including large doses of …

The structure and topology of α-helical coiled coils

AN Lupas, J Bassler, S Dunin-Horkawicz - Fibrous Proteins: Structures and …, 2017 - Springer
Abstract α-Helical coiled coils constitute one of the most diverse folds yet described. They
range in length over two orders of magnitude; they form rods, segmented ropes, barrels …

Chirality transmission in macromolecular domains

S Pandey, S Mandal, MB Danielsen, A Brown… - Nature …, 2022 - nature.com
Chiral communications exist in secondary structures of foldamers and copolymers via a
network of noncovalent interactions within effective intermolecular force (IMF) range. It is not …

The SDBC is active in quenching oxidative conditions and bridges the cell envelope layers in Deinococcus radiodurans

D Farci, AT Graça, L Iesu, D de Sanctis… - Journal of Biological …, 2023 - ASBMB
Deinococcus radiodurans is known for its remarkable ability to withstand harsh stressful
conditions. The outermost layer of its cell envelope is a proteinaceous coat, the S-layer …

Human LINE-1 retrotransposition requires a metastable coiled coil and a positively charged N-terminus in L1ORF1p

E Khazina, O Weichenrieder - Elife, 2018 - elifesciences.org
LINE-1 (L1) is an autonomous retrotransposon, which acted throughout mammalian
evolution and keeps contributing to human genotypic diversity, genetic disease and cancer …

A library of coiled-coil domains: from regular bundles to peculiar twists

K Szczepaniak, A Bukala, AM da Silva Neto… - …, 2020 - academic.oup.com
Motivation Coiled coils are widespread protein domains involved in diverse processes
ranging from providing structural rigidity to the transduction of conformational changes. They …

Functional and structural roles of coiled coils

MD Hartmann - Fibrous Proteins: Structures and Mechanisms, 2017 - Springer
Coiled coils appear in countless structural contexts, as appendages to small proteins, as
parts of multi-domain proteins, and as building blocks of filaments. Although their structure is …

Characterization of MCU-binding proteins MCUR1 and CCDC90B—representatives of a protein family conserved in prokaryotes and eukaryotic organelles

J Adlakha, I Karamichali, J Sangwallek, S Deiss, K Bär… - Structure, 2019 - cell.com
Membrane-bound coiled-coil proteins are important mediators of signaling, fusion, and
scaffolding. Here, we delineate a heterogeneous group of trimeric membrane-anchored …