To execute the intricate process of development, cells coordinate across tissues and organs
to determine where each cell divides and differentiates. This coordination requires complex …

Decoding how tissue properties emerge across multiple spatial and temporal scales from
the integration of local signals is a grand challenge in quantitative biology. For example, the …

Skin homeostasis is maintained by stem cells, which must communicate to balance their
regenerative behaviors. Yet, how adult stem cells signal across regenerative tissue remains …

The robust specification of organ development depends on coordinated cell-cell
communication. This process requires signal integration among multiple pathways, relying …

Simple Summary Eyespot foci on butterfly wings function as organizers for eyespot color
patterns during development. Here, we microscopically examined the scales, sockets, and …

The diversity in the color patterns of butterfly wings is one of the most spectacular and
mysterious puzzles of and unsolved problems in nature. Most of the 15,000 or so species of …

Background One hypothesis surrounding the origin of novel traits is that they originate from
the co-option of pre-existing genes or larger gene regulatory networks into novel …

Information flow within and between cells depends significantly on calcium (Ca2+) signaling
dynamics. However, the biophysical mechanisms that govern emergent patterns of Ca2+ …

Simple Summary Chitin is the major component in the extracellular cuticle and plays
multiple roles in insects. In butterflies, chitin contributes to the development of scales and …

Corals build their skeletons using extracellular calcifying fluid located in the tissue–skeleton
interface. However, the mechanism by which corals control the transport of calcium and …