Stem cell-based therapy for human diseases

DM Hoang, PT Pham, TQ Bach, ATL Ngo… - Signal transduction and …, 2022 - nature.com
Recent advancements in stem cell technology open a new door for patients suffering from
diseases and disorders that have yet to be treated. Stem cell-based therapy, including …

Translational applications of hydrogels

S Correa, AK Grosskopf, H Lopez Hernandez… - Chemical …, 2021 - ACS Publications
Advances in hydrogel technology have unlocked unique and valuable capabilities that are
being applied to a diverse set of translational applications. Hydrogels perform functions …

[HTML][HTML] Articular cartilage and osteochondral tissue engineering techniques: Recent advances and challenges

W Wei, H Dai - Bioactive materials, 2021 - Elsevier
In spite of the considerable achievements in the field of regenerative medicine in the past
several decades, osteochondral defect regeneration remains a challenging issue among …

Cell therapy: types, regulation, and clinical benefits

AEH El-Kadiry, M Rafei, R Shammaa - Frontiers in Medicine, 2021 - frontiersin.org
Cell therapy practices date back to the 19th century and continue to expand on
investigational and investment grounds. Cell therapy includes stem cell-and non–stem cell …

Biological functions of mesenchymal stem cells and clinical implications

A Naji, M Eitoku, B Favier, F Deschaseaux… - Cellular and Molecular …, 2019 - Springer
Mesenchymal stem cells (MSCs) are isolated from multiple biological tissues—adult bone
marrow and adipose tissues and neonatal tissues such as umbilical cord and placenta. In …

Trends in mesenchymal stem cell clinical trials 2004-2018: Is efficacy optimal in a narrow dose range?

M Kabat, I Bobkov, S Kumar… - Stem cells translational …, 2020 - academic.oup.com
The number of clinical trials using mesenchymal stem cells (MSCs) has increased since
2008, but this trend slowed in the past several years and dropped precipitously in 2018 …

Sources and clinical applications of mesenchymal stem cells: state-of-the-art review

R Berebichez-Fridman… - Sultan Qaboos …, 2018 - pmc.ncbi.nlm.nih.gov
First discovered by Friedenstein in 1976, mesenchymal stem cells (MSCs) are adult stem
cells found throughout the body that share a fixed set of characteristics. Discovered initially …

Cell-based drug delivery systems and their in vivo fate

L Yang, Y Yang, Y Chen, Y Xu, J Peng - Advanced Drug Delivery Reviews, 2022 - Elsevier
Cell-based drug delivery systems (DDSs) have received attention recently because of their
unique biological properties and self-powered functions, such as excellent biocompatibility …

Cell membrane-coated mimics: a methodological approach for fabrication, characterization for therapeutic applications, and challenges for clinical translation

V Chugh, K Vijaya Krishna, A Pandit - ACS nano, 2021 - ACS Publications
Cell membrane-coated (CMC) mimics are micro/nanosystems that combine an isolated cell
membrane and a template of choice to mimic the functions of a cell. The design exploits its …

The therapeutic potential of mesenchymal stem cells for cardiovascular diseases

Y Guo, Y Yu, S Hu, Y Chen, Z Shen - Cell Death & Disease, 2020 - nature.com
Mesenchymal stem cells (MSCs) are derived from a wide range of sources and easily
isolated and cultured. MSCs have the capacity for in vitro amplification and self-renewal, low …