ANCA-associated vasculitis

AR Kitching, HJ Anders, N Basu, E Brouwer… - Nature reviews Disease …, 2020 - nature.com
The anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAVs) are a
group of disorders involving severe, systemic, small-vessel vasculitis and are characterized …

Pathogenesis and therapeutic interventions for ANCA-associated vasculitis

D Nakazawa, S Masuda, U Tomaru… - Nature Reviews …, 2019 - nature.com
Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) affects systemic
small vessels and is accompanied by the presence of ANCAs in the serum. This disease …

Genomic atlas of the human plasma proteome

BB Sun, JC Maranville, JE Peters, D Stacey, JR Staley… - Nature, 2018 - nature.com
Although plasma proteins have important roles in biological processes and are the direct
targets of many drugs, the genetic factors that control inter-individual variation in plasma …

Revised 2017 international consensus on testing of ANCAs in granulomatosis with polyangiitis and microscopic polyangiitis

X Bossuyt, JW Cohen Tervaert, Y Arimura… - Nature Reviews …, 2017 - nature.com
Anti-neutrophil cytoplasmic antibodies (ANCAs) are valuable laboratory markers used for
the diagnosis of well-defined types of small-vessel vasculitis, including granulomatosis with …

ANCA glomerulonephritis and vasculitis

JC Jennette, PH Nachman - … Journal of the American Society of …, 2017 - journals.lww.com
ANCA vasculitis has an associated autoimmune response that produces ANCAs that induce
distinct pathologic lesions. Pauci-immune necrotizing and crescentic GN is a frequent …

Overview of the 2012 revised International Chapel Hill Consensus Conference nomenclature of vasculitides

JC Jennette - Clinical and experimental nephrology, 2013 - Springer
The nomenclature and classification of vasculitis has been difficult and controversial for
many decades. This is problematic both for research on vasculitis as well as clinical care of …

ANCA-associated vasculitis: an update

S Almaani, LA Fussner, S Brodsky, AS Meara… - Journal of clinical …, 2021 - mdpi.com
Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) represents a group
of small vessel vasculitides characterized by granulomatous and neutrophilic tissue …

The immune system and kidney disease: basic concepts and clinical implications

C Kurts, U Panzer, HJ Anders, AJ Rees - Nature Reviews Immunology, 2013 - nature.com
The kidneys are frequently targeted by pathogenic immune responses against renal
autoantigens or by local manifestations of systemic autoimmunity. Recent studies in rodent …

Cardiovascular disease in patients with chronic inflammation: mechanisms underlying premature cardiovascular events in rheumatologic conditions

JC Mason, P Libby - European heart journal, 2015 - academic.oup.com
A variety of systemic inflammatory rheumatic diseases associate with an increased risk of
atherosclerotic events and premature cardiovascular (CV) disease. Although this recognition …

[HTML][HTML] EULAR recommendations for the management of ANCA-associated vasculitis: 2022 update

B Hellmich, B Sanchez-Alamo, JH Schirmer… - Annals of the …, 2024 - ard.bmj.com
Background Since the publication of the EULAR recommendations for the management of
antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) in 2016, several …