Deep learning methods for drug response prediction in cancer: predominant and emerging trends

A Partin, TS Brettin, Y Zhu, O Narykov, A Clyde… - Frontiers in …, 2023 - frontiersin.org
Cancer claims millions of lives yearly worldwide. While many therapies have been made
available in recent years, by in large cancer remains unsolved. Exploiting computational …

Trends and potential of machine learning and deep learning in drug study at single-cell level

R Qi, Q Zou - Research, 2023 - spj.science.org
Cancer treatments always face challenging problems, particularly drug resistance due to
tumor cell heterogeneity. The existing datasets include the relationship between gene …

GraphCDR: a graph neural network method with contrastive learning for cancer drug response prediction

X Liu, C Song, F Huang, H Fu, W ** single-cell sequencing analyses produce more comprehensive profiles
of the genomic, transcriptomic, and epigenomic heterogeneity of tumor subpopulations than …

Auto-HMM-LMF: feature selection based method for prediction of drug response via autoencoder and hidden Markov model

A Emdadi, C Eslahchi - BMC bioinformatics, 2021 - Springer
Background Predicting the response of cancer cell lines to specific drugs is an essential
problem in personalized medicine. Since drug response is closely associated with genomic …