Endometrial hyperplasia

KL Ring, AM Mills, SC Modesitt - Obstetrics & Gynecology, 2022‏ - journals.lww.com
The objectives of this Clinical Expert Series on endometrial hyperplasia are to review the
etiology and risk factors, histologic classification and subtypes, malignant progression risks …

[HTML][HTML] Metabolic reprogramming and interventions in endometrial carcinoma

J Li, H Yang, L Zhang, S Zhang, Y Dai - Biomedicine & Pharmacotherapy, 2023‏ - Elsevier
Cancer cells are usually featured by metabolic adaptations that facilitate their growth,
invasion, and metastasis. Thus, reprogramming of intracellular energy metabolism is …

Fertility-sparing approaches in atypical endometrial hyperplasia and endometrial cancer patients: current evidence and future directions

NA Contreras, J Sabadell, P Verdaguer, C Julià… - International journal of …, 2022‏ - mdpi.com
Endometrial cancer (EC) is the fourth most common cancer in women in developed
countries. Although it is usually diagnosed in postmenopausal women, its incidence has …

Live births and maintenance with levonorgestrel IUD improve disease-free survival after fertility-sparing treatment of atypical hyperplasia and early endometrial cancer

OV Novikova, VB Nosov, VA Panov, EG Novikova… - Gynecologic …, 2021‏ - Elsevier
Objective Our objectives were to (1) compare different regimens of hormonal therapy (HT) in
young women with atypical endometrial hyperplasia (AEH) and early endometrial cancer …

[HTML][HTML] Outcomes of women treated with progestin and metformin for atypical endometrial hyperplasia and early endometrial cancer: a systematic review and meta …

J Chae-Kim, G Garg, L Gavrilova-Jordan… - International Journal of …, 2021‏ - Elsevier
Objective Progestin therapy is the recommended fertility-sparing management of atypical
endometrial hyperplasia or early-stage endometrial cancer in reproductive-aged women …

[HTML][HTML] Conservative management of atypical endometrial hyperplasia and early endometrial cancer in childbearing age women

S Uccella, PC Zorzato, S Dababou, M Bosco, M Torella… - Medicina, 2022‏ - mdpi.com
Total hysterectomy and bilateral adnexectomy is the standard treatment for atypical
endometrial hyperplasia and early-stage endometrial cancer. However, the recommended …

Fertility-sparing treatment of patients with endometrial cancer: a review of the literature

U Leone Roberti Maggiore, R Khamisy-Farah… - Journal of clinical …, 2021‏ - mdpi.com
Endometrial cancer (EC) is currently the most common malignancy of the female genital tract
in developed countries. Although it is more common in postmenopausal women, it may …

A prospective cohort study of metformin as an adjuvant therapy for infertile women with endometrial complex hyperplasia/complex atypical hyperplasia and their …

W Kong, Z Liu, N Zhang, X Wu, X Zhao… - Frontiers in …, 2022‏ - frontiersin.org
Objective To investigate the adjuvant efficacy of metformin treatment to achieve pathological
complete response (CR) in patients with endometrial complex hyperplasia (CH) and …

The potential role of GLP-1 receptor agonist targeting in fertility-sparing treatment in obese patients with endometrial malignant pathology: a call for research

CJ Violette, R Agarwal, RS Mandelbaum… - Expert Review of …, 2023‏ - Taylor & Francis
Introduction Most patients diagnosed with endometrial hyperplasia or cancer are obese.
Obesity, along with polycystic ovarian syndrome (PCOS) and type-2 diabetes mellitus …

[HTML][HTML] The perspectives of fertility preservation in women with endometrial cancer

J Knez, L Al Mahdawi, I Takač, M Sobočan - Cancers, 2021‏ - mdpi.com
Simple Summary Endometrial cancer is a common gynecological malignant disease. Its
incidence in women of reproductive age in developed countries is increasing. The standard …