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Occurrence and spatial distribution of pharmaceuticals and personal care products (PPCPs) in the aquatic environment, their characteristics, and adopted legislations
Pharmaceuticals and personal care products (PPCPs) residues are known to occur widely in
the aquatic environments of industrialized and develo** countries. Considerable progress …
the aquatic environments of industrialized and develo** countries. Considerable progress …
Regulatory updates and analytical methodologies for nitrosamine impurities detection in sartans, ranitidine, nizatidine, and metformin along with sample preparation …
KM Shaik, B Sarmah, GS Wadekar… - Critical reviews in …, 2022 - Taylor & Francis
Nitrosamine impurities have been detected in various pharmaceutical products in recent
days. Various sartans, ranitidine, nizatidine, and metformin have been recalled from the …
days. Various sartans, ranitidine, nizatidine, and metformin have been recalled from the …
Sustainable chromatographic quantitation of multi-antihypertensive medications: application on diverse combinations containing hydrochlorothiazide along with LC …
Cardiovascular disorders are among the leading causes of death worldwide, especially
hypertension, a silent killer syndrome requiring multiple drug therapy for appropriate …
hypertension, a silent killer syndrome requiring multiple drug therapy for appropriate …
Establishment of human induced pluripotent stem cell-derived hepatobiliary organoid with bile duct for pharmaceutical research use
L Wang, Y Koui, K Kanegae, T Kido, M Tamura-Nakano… - Biomaterials, 2024 - Elsevier
In vitro models of the human liver are promising alternatives to animal tests for drug
development. Currently, primary human hepatocytes (PHHs) are preferred for …
development. Currently, primary human hepatocytes (PHHs) are preferred for …
Valsartan as a prophylactic treatment against breast cancer development and niche activation: What molecular sequels follow chronic AT-1R blockade?
Aims Transactivation of insulin-growth-factor-receptor (IGF-1R) by angiotensin-II-type-1-
receptor (AT-1R) was only demonstrated in vascular-smooth-muscle cells and has never …
receptor (AT-1R) was only demonstrated in vascular-smooth-muscle cells and has never …
Synthesis of molecularly imprinted polymer as a nanosorbent for dispersive magnetic micro solid-phase extraction and determination of valsartan in biological …
N Azizi-Khereshki, HZ Mousavi, MG Dogaheh… - … Acta Part A: Molecular …, 2023 - Elsevier
A magnetic molecularly imprinted polymer (MIP) was synthesized by precipitation
polymerization utilizing Fe 3 O 4@ SiO 2-MPS as a magnetic core, itaconic acid as a …
polymerization utilizing Fe 3 O 4@ SiO 2-MPS as a magnetic core, itaconic acid as a …
Clinical pharmacokinetics of sacubitril/valsartan (LCZ696): a novel angiotensin receptor-neprilysin inhibitor
S Ayalasomayajula, T Langenickel, P Pal… - Clinical …, 2017 - Springer
Abstract Sacubitril/valsartan (LCZ696) is indicated for the treatment of heart failure with
reduced ejection fraction. Absorption of sacubitril/valsartan and conversion of sacubitril …
reduced ejection fraction. Absorption of sacubitril/valsartan and conversion of sacubitril …
Understanding flow chemistry for the production of active pharmaceutical ingredients
Multi-step organic syntheses of various drugs, active pharmaceutical ingredients, and other
pharmaceutically and agriculturally important compounds have already been reported using …
pharmaceutically and agriculturally important compounds have already been reported using …
A multi-analyte LC-MS/MS method for screening and quantification of nitrosamines in sartans
SH Chang, CC Chang, LJ Wang… - Journal of Food and …, 2020 - pmc.ncbi.nlm.nih.gov
An incident of sartan medicine contamination was notified by Europe in June 2018. The
contaminant was identified as a probable carcinogenic nitrosamine and the recalls of sartan …
contaminant was identified as a probable carcinogenic nitrosamine and the recalls of sartan …
[PDF][PDF] A review on candesartan: pharmacological and pharmaceutical profile
A Husain, MS Azim, M Mitra… - Journal of Applied …, 2011 - japsonline.com
Candesartan is classified as an angiotensin II receptor type 1 antagonist. Angiotensin II
receptor type 1 antagonists are widely used in treatment of diseases like hypertension, heart …
receptor type 1 antagonists are widely used in treatment of diseases like hypertension, heart …