Cardiorenal syndromes have been categorized into 5 clinical subtypes based on which
organ is perceived to be the primary precipitant of the vicious and interrelated cycle of …

Diabetic kidney disease (DKD) is a major public health problem characterized by elevated
urine albumin excretion or reduced glomerular filtration rate or both. The pathophysiology of …

Myocardial fibrosis (MF) plays a key role in the development and progression of heart failure
(HF) with limited effective therapies. Galectin-3 (Gal-3) is a biomarker associated with …

Modified citrus pectin (MCP) has a low-molecular-weight degree of esterification to allow
absorption from the small intestinal epithelium into the circulation. MCP produces pleiotropic …

The anticancer activity of pectic polysaccharides (PPs) was proved by numerous studies,
and which also indicated that the bioactivity of PPs was closely related to its complicated …

Galectin-3 (Gal-3) is a 30KDa lectin implicated in multiple pathophysiology pathways
including renal damage and fibrosis. Gal-3 binds β-galactoside through its carbohydrate …

Thromboembolic complications and excessive inflammation are frequent in severe COVID-
19, potentially leading to long COVID. In non-COVID studies, we and others demonstrated …

Galectin-3 has been proposed as a novel biomarker of heart failure and cardiac fibrosis, and
may also be associated with fibrosis of other organs such as the kidney. To determine this …

Renal fibrogenesis is the common final pathway to all renal injuries that consequently leads
to Chronic Kidney Disease (CKD). Renal fibrogenesis corresponds to the replacement of …

Galectin-3 and Suppression of tumorigenicity-2 (ST2) are known markers of cardiac fibrosis.
We investigated the prognostic value of fibrotic markers for the development of diastolic …