[HTML][HTML] The CRISPR-Cas toolbox and gene editing technologies

G Liu, Q Lin, S **, C Gao - Molecular cell, 2022 - cell.com
The emergence of CRISPR-Cas systems has accelerated the development of gene editing
technologies, which are widely used in the life sciences. To improve the performance of …

Lateral flow test engineering and lessons learned from COVID-19

J Budd, BS Miller, NE Weckman, D Cherkaoui… - Nature Reviews …, 2023 - nature.com
The acceptability and feasibility of large-scale testing with lateral flow tests (LFTs) for clinical
and public health purposes has been demonstrated during the COVID-19 pandemic. LFTs …

Minimally instrumented SHERLOCK (miSHERLOCK) for CRISPR-based point-of-care diagnosis of SARS-CoV-2 and emerging variants

H De Puig, RA Lee, D Najjar, X Tan, LR Soenksen… - Science …, 2021 - science.org
The COVID-19 pandemic highlights the need for diagnostics that can be rapidly adapted
and deployed in a variety of settings. Several SARS-CoV-2 variants have shown worrisome …

Electrochemical biosensor for nucleic acid amplification-free and sensitive detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA via …

W Heo, K Lee, S Park, KA Hyun, HI Jung - Biosensors and Bioelectronics, 2022 - Elsevier
The outbreak of the COVID-19 pandemic has led to millions of fatalities worldwide. For
preventing epidemic transmission, rapid and accurate virus detection methods to early …

Asymmetric CRISPR enabling cascade signal amplification for nucleic acid detection by competitive crRNA

J Moon, C Liu - Nature Communications, 2023 - nature.com
Nucleic acid detection powered by CRISPR technology provides a rapid, sensitive, and
deployable approach to molecular diagnostics. While exciting, there remain challenges …

A strategy combining 3D-DNA Walker and CRISPR-Cas12a trans-cleavage activity applied to MXene based electrochemiluminescent sensor for SARS-CoV-2 RdRp …

K Zhang, Z Fan, Y Huang, Y Ding, M **e - Talanta, 2022 - Elsevier
Early diagnosis and timely management of Severe Acute Respiratory Syndrome
Coronavirus 2 (SARS-CoV-2) are the keys to preventing the spread of the epidemic and …