Emerging evidence for astrocyte dysfunction in schizophrenia

EC de Oliveira Figueiredo, C Calì, F Petrelli, P Bezzi - Glia, 2022 - Wiley Online Library
Schizophrenia is a complex, chronic mental health disorder whose heterogeneous genetic
and neurobiological background influences early brain development, and whose precise …

Epigenetic targets in schizophrenia development and therapy

A Wawrzczak-Bargieła, W Bilecki, M Maćkowiak - Brain Sciences, 2023 - mdpi.com
Schizophrenia is regarded as a neurodevelopmental disorder with its course progressing
throughout life. However, the aetiology and development of schizophrenia are still under …

Effects of MAO-B inhibitors on non-motor symptoms and quality of life in Parkinson's disease: A systematic review

T Tsuboi, Y Satake, K Hiraga, K Yokoi, M Hattori… - npj Parkinson's …, 2022 - nature.com
Non-motor symptoms (NMS) are common among patients with Parkinson's disease and
reduce patients' quality of life (QOL). However, there remain considerable unmet needs for …

Assessment and treatment of negative symptoms in schizophrenia—A regional perspective

I Bitter, P Mohr, N Raspopova, A Szulc… - Frontiers in …, 2022 - frontiersin.org
Clinicians and researchers consider that there are a variety of symptoms that constitute
negative symptoms in schizophrenia, and they may use different definitions for the same …

Stratification by sex and hormone level when contrasting men and women in schizophrenia trials will improve personalized treatment

MV Seeman, A González-Rodríguez - Journal of Personalized Medicine, 2021 - mdpi.com
Background: Sex and gender differences have been reported in the prevalence, expression,
treatment response, and outcome of schizophrenia, but most reports are based on relatively …

Gene expression and epigenetic regulation in the prefrontal cortex of schizophrenia

W Bilecki, M Maćkowiak - Genes, 2023 - mdpi.com
Schizophrenia pathogenesis remains challenging to define; however, there is strong
evidence that the interaction of genetic and environmental factors causes the disorder. This …

[HTML][HTML] Dopaminergic Epistases in Schizophrenia

A Bosun, R Albu-Kalinovic, O Neda-Stepan, I Bosun… - Brain Sciences, 2024 - mdpi.com
Background: The dopaminergic theory, the oldest and most comprehensively analyzed
neurotransmitter theory of schizophrenia, remains a focal point of research. Methods: This …

A preliminary study on the association of single nucleotide polymorphisms and methylation of dopamine system‐related genes with psychotic symptoms in patients …

T Fang, MN Liu, MQ Liu, XY Tian… - European Journal of …, 2024 - Wiley Online Library
Methamphetamine use disorder (MAUD) can substantially jeopardize public security due to
its high‐risk social psychology and behaviour. Given that the dopamine reward system is …

The effect of vortioxetine on anhedonia in patients with schizophrenia

A Greš, M Šagud, A Dickov - The International Journal of …, 2024 - journals.sagepub.com
Objective Anhedonia is a common symptom of depression, but is also a negative symptom
of schizophrenia. The purpose of this study was to examine the effects of vortioxetine on …