[HTML][HTML] KRAS as a key oncogene in the clinical precision diagnosis and treatment of pancreatic cancer
M Dai, S Chen, X Teng, K Chen, W Cheng - Journal of Cancer, 2022 - ncbi.nlm.nih.gov
Pancreatic ductal adenocarcinoma (PDAC) is one of the most malignant tumors, with a 5-
year survival rate of less than 10%. At present, the comprehensive treatment based on …
year survival rate of less than 10%. At present, the comprehensive treatment based on …
Hippo pathway in non-small cell lung cancer: mechanisms, potential targets, and biomarkers
H Liang, Y Xu, J Zhao, M Chen, M Wang - Cancer Gene Therapy, 2024 - nature.com
Lung cancer is the primary contributor to cancer-related deaths globally, and non-small cell
lung cancer (NSCLC) constitutes around 85% of all lung cancer cases. Recently, the …
lung cancer (NSCLC) constitutes around 85% of all lung cancer cases. Recently, the …
The significance of Hippo pathway protein expression in oral squamous cell carcinoma
Introduction The Hippo pathway consists of mammalian sterile 20-like kinase 1/2 (MST1/2),
large tumor suppressor 1/2 (LATS1/2), and yes-associated protein (YAP) 1. Herein, we …
large tumor suppressor 1/2 (LATS1/2), and yes-associated protein (YAP) 1. Herein, we …
[HTML][HTML] A Theoretical Study on the Efficacy and Mechanism of Combined YAP-1 and PARP-1 Inhibitors in the Treatment of Glioblastoma Multiforme Using Peruvian …
AG Turpo-Peqqueña, S Luna-Prado… - Current Issues in …, 2025 - mdpi.com
Glioblastoma multiforme (GBM) is one of the most aggressive and treatment-resistant forms
of brain cancer. Current therapeutic strategies, including surgery, chemotherapy, and …
of brain cancer. Current therapeutic strategies, including surgery, chemotherapy, and …
Pathological Significance of Kidney and Brain Expressed Protein (KIBRA) in Clear Cell Renal Cell Carcinoma
Y Nagashima, K Mitsunari, T Matsuo… - Anticancer …, 2023 - ar.iiarjournals.org
Background/Aim: Kidney and brain expressed protein (KIBRA), a member of the WW domain-
containing protein family, has an important role in tumour growth and progression in various …
containing protein family, has an important role in tumour growth and progression in various …
STK3 kinase activation inhibits tumor proliferation through FOXO1-TP53INP1/P21 pathway in esophageal squamous cell carcinoma
Z Zhao, Y Chu, A Feng, S Zhang, H Wu, Z Li, M Sun… - Cellular Oncology, 2024 - Springer
Purpose Esophageal squamous cell carcinoma (ESCC) is an aggressive disease with a
poor prognosis, caused by the inactivation of critical cell growth regulators that lead to …
poor prognosis, caused by the inactivation of critical cell growth regulators that lead to …
NF-κB Mediated Disruption of Pancreatic Signaling Pathways and its Implications for the Risk of Pancreatic Adenocarcinoma: a systematic review
O Shafi, R Rajpar, FNU Aakash, M Waqas, M Haseeb… - medRxiv, 2024 - medrxiv.org
Objective: The objective of this study is to determine how NF-kappa B-mediated
inflammation disrupts pancreatic signaling pathways and the resultant increase in the risk of …
inflammation disrupts pancreatic signaling pathways and the resultant increase in the risk of …
TEAD3 inhibits the proliferation and metastasis of prostate cancer via suppressing ADRBK2
C Wang, S Chen, X Li, L Fan, Z Zhou, M Zhang… - Biochemical and …, 2023 - Elsevier
TEAD3 acts as a transcription factor in many tumors to promote tumor occurrence and
development. But in prostate cancer (PCa), it appears as a tumor suppressor gene. Recent …
development. But in prostate cancer (PCa), it appears as a tumor suppressor gene. Recent …
Evaluation of the significance of human class I homeobox A13 and STK4/MST1 expression in conventional colorectal adenoma and adenocarcinoma and correlation …
EM Abdel-Aal, AES Soliman - Egyptian Journal of Pathology, 2022 - journals.lww.com
Background Colorectal carcinoma (CRC) is the third most common cancer in the world.
Human class I homeobox A13 (HOXA13) was initially identified as a transcription factor and …
Human class I homeobox A13 (HOXA13) was initially identified as a transcription factor and …