The immunological synapse
SK Bromley, WR Burack, KG Johnson… - Annual review of …, 2001 - annualreviews.org
The adaptive immune response is initiated by the interaction of T cell antigen receptors with
major histocompatibility complex molecule-peptide complexes in the nanometer scale gap …
major histocompatibility complex molecule-peptide complexes in the nanometer scale gap …
Dynamic, yet structured: the cell membrane three decades after the Singer–Nicolson model
The fluid mosaic membrane model proved to be a very useful hypothesis in explaining
many, but certainly not all, phenomena taking place in biological membranes. New …
many, but certainly not all, phenomena taking place in biological membranes. New …
Metformin enhances autophagy and normalizes mitochondrial function to alleviate aging-associated inflammation
Age is a non-modifiable risk factor for the inflammation that underlies age-associated
diseases; thus, anti-inflammaging drugs hold promise for increasing health span. Cytokine …
diseases; thus, anti-inflammaging drugs hold promise for increasing health span. Cytokine …
Mediators of innate immune recognition of bacteria concentrate in lipid rafts and facilitate lipopolysaccharide-induced cell activation
M Triantafilou, K Miyake, DT Golenbock… - Journal of cell …, 2002 - journals.biologists.com
The plasma membrane of cells is composed of lateral heterogeneities, patches and
microdomains. These membrane microdomains or lipid rafts are enriched in …
microdomains. These membrane microdomains or lipid rafts are enriched in …
Adiponectin modulates inflammatory reactions via calreticulin receptor–dependent clearance of early apoptotic bodies
Y Takemura, N Ouchi, R Shibata, T Aprahamian… - The Journal of clinical …, 2007 - jci.org
Obesity and type 2 diabetes are associated with chronic inflammation. Adiponectin is an
adipocyte-derived hormone with antidiabetic and antiinflammatory actions. Here, we …
adipocyte-derived hormone with antidiabetic and antiinflammatory actions. Here, we …
Monomeric IgE stimulates signaling pathways in mast cells that lead to cytokine production and cell survival
J Kalesnikoff, M Huber, V Lam, JE Damen, J Zhang… - Immunity, 2001 - cell.com
Although IgE binding to mast cells is thought to be a passive presensitization step, we
demonstrate herein that monomeric IgE (mIgE) in the absence of antigen (Ag) stimulates …
demonstrate herein that monomeric IgE (mIgE) in the absence of antigen (Ag) stimulates …
[PDF][PDF] T cells and aging, January 2002 update
[Frontiers in Bioscience 7, d1056-1183, May 1, 2002] 1056 T CELLS AND AGING,
JANUARY 2002 UPDATE Graham Pawelec1, Yvonne Barnett Page 1 [Frontiers in …
JANUARY 2002 UPDATE Graham Pawelec1, Yvonne Barnett Page 1 [Frontiers in …
Lipid rafts and HIV-1: from viral entry to assembly of progeny virions
Background: Lipid rafts are currently an intensely investigated topic of cell biology. In
addition to a demonstrated role in signal transduction of the host cell, lipid rafts serve as …
addition to a demonstrated role in signal transduction of the host cell, lipid rafts serve as …
Dynamics of the actin cytoskeleton mediates receptor cross talk: An emerging concept in tuning receptor signaling
Recent evidence implicates the actin cytoskeleton in the control of receptor signaling. This
may be of particular importance in the context of immune receptors, such as the B cell …
may be of particular importance in the context of immune receptors, such as the B cell …
Microdomains of the C-type lectin DC-SIGN are portals for virus entry into dendritic cells
The C-type lectin dendritic cell (DC)–specific intercellular adhesion molecule grabbing non-
integrin (DC-SIGN; CD209) facilitates binding and internalization of several viruses …
integrin (DC-SIGN; CD209) facilitates binding and internalization of several viruses …