Targeting fibroblast-endothelial interactions in LAM pathogenesis using 3D spheroid models and spatial transcriptomics

S Koc-Gunel, EC Liu, LK Gautam, BA Calvert, S Murthy… - JCI insight, 2025 - insight.jci.org
Lymphangioleiomyomatosis (LAM) is a progressive lung disease with limited treatments,
largely due to an incomplete understanding of its pathogenesis. Lymphatic endothelial cells …

Exosomal miR-6126 as a novel therapeutic target for overcoming resistance of anti-cancer effect in hepatocellular carcinoma

H Hwang, J Kim, TH Kim, Y Han, D Choi, S Cho, S Kim… - BMC cancer, 2024 - Springer
Background Hepatocellular carcinoma (HCC) stands as the sixth most prevalent cancer
globally, presenting a substantial health challenge, particularly due to late-stage diagnoses …