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The evolution of drug metabolism
DW Nebert, MZ Dieter - Pharmacology, 2000 - karger.com
So-called 'drug-metabolizing enzyme'(DME) genes have existed on this planet for more than
2.5 billion years and would be more appropriately named 'effector-metabolizing enzymes' …
2.5 billion years and would be more appropriately named 'effector-metabolizing enzymes' …
Генетический паспорт-основа индивидуальной и предиктивной медицины
ВС Баранов, АС Глотов, ТЭ Иващенко, ОС Глотов… - 2009 - elibrary.ru
В доступной форме в книге изложены основные события, произошедшие в
медицинской генетике и в молекулярной медицине после расшифровки генома …
медицинской генетике и в молекулярной медицине после расшифровки генома …
[КНИГА][B] Guide to cytochromes P450: structure and function
DFV Lewis - 1996 - taylorfrancis.com
This book covers the relevant aspects of cytochromes P450 for understanding their structure,
function and mechanisms of action, such as physicochemical characterization methods …
function and mechanisms of action, such as physicochemical characterization methods …
Glutathione‐S‐transferase gene polymorphisms (GSTT1, GSTM1, GSTP1) as increased risk factors for asthma
Objectives: Asthma is a complex multifactorial disease with an obvious genetic
predisposition, immunological aberration, and involvement of noxious environmental factors …
predisposition, immunological aberration, and involvement of noxious environmental factors …
Glutathione-S-transferase µ and theta gene polymorphisms as new risk factors of atopic bronchial asthma
T Ivaschenko, O Sideleva, V Baranov - Journal of molecular medicine, 2002 - Springer
The genetic polymorphism of glutathione-S-transferase M1 (GSTM1) and glutathione-S-
transferase T1 (GSTT1) genes and the cytochrome P4501A1 gene responsible for …
transferase T1 (GSTT1) genes and the cytochrome P4501A1 gene responsible for …
Ethnic and genetic differences in metabolism genes and risk of toxicity and cancer
DW Nebert, AL Roe - Science of the Total Environment, 2001 - Elsevier
Individual risk of toxicity or cancer can be affected by one's exposure to sufficiently high
doses of particular environmental agents (or mixtures), combined with each person's …
doses of particular environmental agents (or mixtures), combined with each person's …
The Glutathione S-Transferase-μ and -θ Genotypes in the Etiology of Prostate Cancer: Genotype-Environment Interactions with Smoking
SN Kelada, SLR Kardia, AH Walker… - Cancer Epidemiology …, 2000 - aacrjournals.org
It has been reported that individuals who express GSTT1, the gene coding for the θ class of
the glutathione S-transferases (GSTs), have an elevated risk of prostate cancer (CaP). This …
the glutathione S-transferases (GSTs), have an elevated risk of prostate cancer (CaP). This …
Определение генетической предрасположенности к некоторым мультифакториальным заболеваниям. Генетический паспорт
ТЭ Иващенко, ДЛ Стрекалов, ДВ Соловьева… - 2001 - elibrary.ru
Методические рекомендации подготовлены на основании результатов научных
исследований и внедрения в медицинскую практику молекулярно-генетических …
исследований и внедрения в медицинскую практику молекулярно-генетических …
Роль генетических факторов в развитии различных нозологических форм врожденных расщелин губы и неба.
СВ Чуйкин, ДИ Шайхутдинова… - Вестник Башкирского …, 2006 - cyberleninka.ru
В данной статье представлены результаты изучения возможной роли генов,
ответственных за детоксикацию ксенобиотиков, в развитии различных клинических …
ответственных за детоксикацию ксенобиотиков, в развитии различных клинических …
Pharmacogenetics and pharmacogenomics
DW Nebert - e LS, 2001 - Wiley Online Library
Since we all differ from one another by at least 1 million bases out of the 3.2 billion bases in
our genome, each of us might have variant alleles in most of our genes that affect drug …
our genome, each of us might have variant alleles in most of our genes that affect drug …