The role of ErbB4 in cance r

VFM Segers, L Dugaucquier, E Feyen, H Shakeri… - Cellular oncology, 2020 - Springer
Background The epidermal growth factor receptor family consists of four members, ErbB1
(epidermal growth factor receptor-1), ErbB2, ErbB3, and ErbB4, which all have been found …

From candidate gene studies to GWAS and post-GWAS analyses in breast cancer

L Fachal, AM Dunning - Current opinion in genetics & development, 2015 - Elsevier
There are now more than 90 established breast cancer risk loci, with 57 new ones, revealed
through genome-wide-association studies (GWAS) during the last two years. Established …

Genome-wide association analysis in East Asians identifies breast cancer susceptibility loci at 1q32. 1, 5q14. 3 and 15q26. 1

Q Cai, B Zhang, H Sung, SK Low, SS Kweon, W Lu… - Nature …, 2014 - nature.com
In a three-stage genome-wide association study among East Asian women including 22,780
cases and 24,181 controls, we identified 3 genetic loci newly associated with breast cancer …

Differences in incidence, mortality and survival of breast cancer by regions and countries in Asia and contributing factors

Y Kim, KY Yoo, MT Goodman - Asian Pacific Journal of Cancer …, 2015 - koreascience.kr
Although the incidence of breast cancer in Asia remains lower than in North America,
Western Europe, and Oceania, rates have been increasing rapidly during the past few …

Genome-wide association study of breast cancer in Latinas identifies novel protective variants on 6q25

L Fejerman, N Ahmadiyeh, D Hu, S Huntsman… - Nature …, 2014 - nature.com
The genetic contributions to breast cancer development among Latinas are not well
understood. Here we carry out a genome-wide association study of breast cancer in Latinas …

Identification of novel breast cancer susceptibility loci in meta-analyses conducted among Asian and European descendants

X Shu, J Long, Q Cai, SS Kweon, JY Choi… - Nature …, 2020 - nature.com
Known risk variants explain only a small proportion of breast cancer heritability, particularly
in Asian women. To search for additional genetic susceptibility loci for breast cancer, here …

Genome-and transcriptome-wide association studies of 386,000 Asian and European-ancestry women provide new insights into breast cancer genetics

G Jia, J **, X Shu, Y Yang, Q Cai, SS Kweon… - The American Journal of …, 2022 - cell.com
By combining data from 160,500 individuals with breast cancer and 226,196 controls of
Asian and European ancestry, we conducted genome-and transcriptome-wide association …

A multi-tissue, splicing-based joint transcriptome-wide association study identifies susceptibility genes for breast cancer

G Gao, J McClellan, AN Barbeira, PN Fiorica… - The American Journal of …, 2024 - cell.com
Splicing-based transcriptome-wide association studies (splicing-TWASs) of breast cancer
have the potential to identify susceptibility genes. However, existing splicing-TWASs test the …

Breast cancer family history and contralateral breast cancer risk in young women: an update from the women's environmental cancer and radiation epidemiology study

AS Reiner, J Sisti, EM John, CF Lynch… - Journal of clinical …, 2018 - ascopubs.org
Purpose The Women's Environmental Cancer and Radiation Epidemiology (WECARE)
study demonstrated the importance of breast cancer family history on contralateral breast …

Genome-wide association studies of cancer in diverse populations

SL Park, I Cheng, CA Haiman - Cancer Epidemiology, Biomarkers …, 2018 - aacrjournals.org
Genome-wide association studies (GWAS) of cancer have identified more than 700 risk loci,
of which approximately 80% were first discovered in European ancestry populations …