The glymphatic hypothesis proposes a mechanism for extravascular transport into and out of
the brain of hydrophilic solutes unable to cross the blood–brain barrier. It suggests that there …

Sleep is evolutionarily conserved across all species, and impaired sleep is a common trait of
the diseased brain. Sleep quality decreases as we age, and disruption of the regular sleep …

The brain glymphatic system is involved in the clearance of misfolding α-synuclein, the
impaired glymphatic system may contribute to the progression of Parkinson's disease (PD) …

Background Brain glymphatic dysfunction may contribute to the development of α-
synucleinopathies. Yet, noninvasive imaging and quantification remain lacking. Purpose To …

Parkinson's disease (PD) is a multisystem alpha-synucleinopathic neurodegenerative
disease and the most prevalent neurodegenerative disorder after Alzheimer's disease with a …

The classic concept of the absence of lymphatic vessels in the central nervous system
(CNS), suggesting the immune privilege of the brain in spite of its high metabolic rate, was …

Parkinson's disease (PD) is the second most common age-associated neurodegenerative
disorder and is characterised by progressive loss of dopamine neurons in the substantia …

Objectives This study aimed to evaluate the glymphatic system function in patients with
obstructive sleep apnea (OSA) compared to healthy controls using diffusion tensor imaging …

Slow-wave sleep (SWS) modulation in rodent models of Alzheimer's disease alters
extracellular amyloid burden. In Parkinson's disease (PD), SWS appears to be closely linked …

Introduction Glymphatic dysfunction can contribute to α-synucleinopathies. We examined
glymphatic function in idiopathic Parkinson's disease (PD) utilizing Diffusion Tensor Image …