Protein cages: from fundamentals to advanced applications
Proteins that self-assemble into polyhedral shell-like structures are useful molecular
containers both in nature and in the laboratory. Here we review efforts to repurpose diverse …
containers both in nature and in the laboratory. Here we review efforts to repurpose diverse …
Bacterial microcompartments
Bacterial microcompartments (BMCs) are self-assembling organelles that consist of an
enzymatic core that is encapsulated by a selectively permeable protein shell. The potential …
enzymatic core that is encapsulated by a selectively permeable protein shell. The potential …
The formate bio-economy
O Yishai, SN Lindner, JG de la Cruz… - Current Opinion in …, 2016 - Elsevier
Highlights•Formate is an ideal mediator between the physicochemical and biological
realms.•Formate can be efficiently produced from various highly available …
realms.•Formate can be efficiently produced from various highly available …
[HTML][HTML] Synthetic metabolism: metabolic engineering meets enzyme design
Highlights•Multiple levels of metabolic engineering can be defined, from 'copy and paste'to
various forms of 'synthetic metabolism'.•The biochemical solution space for 'synthetic …
various forms of 'synthetic metabolism'.•The biochemical solution space for 'synthetic …
Assembly, function and evolution of cyanobacterial carboxysomes
Highlights•Alpha and beta carboxysomes differ in composition, assembly, and
evolution.•Alphas appear to co-assemble shell and cargo proteins; betas assemble inside …
evolution.•Alphas appear to co-assemble shell and cargo proteins; betas assemble inside …
A catalog of the diversity and ubiquity of bacterial microcompartments
Bacterial microcompartments (BMCs) are organelles that segregate segments of metabolic
pathways which are incompatible with surrounding metabolism. BMCs consist of a …
pathways which are incompatible with surrounding metabolism. BMCs consist of a …
Bacterial microcompartments and the modular construction of microbial metabolism
Bacterial microcompartments (BMCs) are protein-bound organelles predicted to be present
across 23 bacterial phyla. BMCs facilitate carbon fixation as well as the aerobic and …
across 23 bacterial phyla. BMCs facilitate carbon fixation as well as the aerobic and …
Bacterial encapsulins as orthogonal compartments for mammalian cell engineering
We genetically controlled compartmentalization in eukaryotic cells by heterologous
expression of bacterial encapsulin shell and cargo proteins to engineer enclosed enzymatic …
expression of bacterial encapsulin shell and cargo proteins to engineer enclosed enzymatic …
Selective molecular transport through the protein shell of a bacterial microcompartment organelle
Bacterial microcompartments are widespread prokaryotic organelles that have important
and diverse roles ranging from carbon fixation to enteric pathogenesis. Current models for …
and diverse roles ranging from carbon fixation to enteric pathogenesis. Current models for …
Programmed loading and rapid purification of engineered bacterial microcompartment shells
Bacterial microcompartments (BMCs) are selectively permeable proteinaceous organelles
which encapsulate segments of metabolic pathways across bacterial phyla. They consist of …
which encapsulate segments of metabolic pathways across bacterial phyla. They consist of …