Lipids play an important role in physiology and pathophysiology of living systems. Until a
few decades ago, the number of lipid molecules that were chemically characterized was a …

Myokit is a new powerful and versatile software tool for modeling and simulation of cardiac
cellular electrophysiology. Myokit consists of an easy-to-read modeling language, a …

Background The increasing use of computational simulation experiments to inform modern
biological research creates new challenges to annotate, archive, share and reproduce such …

Cell migration is central to the development and maintenance of multicellular organisms.
Fundamental understanding of cell migration can, for example, direct novel therapeutic …

Abstract Motivation: The Physiome Model Repository 2 (PMR2) software was created as part
of the IUPS Physiome Project, and today it serves as the foundation for the CellML model …

The VPH/Physiome Project is develo** the model encoding standards CellML (cellml. org)
and FieldML (fieldml. org) as well as web-accessible model repositories based on these …

Computational biologists have been develo** standards and formats for nearly two
decades, with the aim of easing the description and exchange of experimental data …

Metagenomic approaches are increasingly recognized as a baseline for understanding the
ecology and evolution of microbial ecosystems. The development of methods for pathway …

Modern graphics cards contain hundreds of cores that can be programmed for intensive
calculations. They are beginning to be used for spiking neural network simulations. The goal …

Objective: Like all scientific research, computational neuroscience research must be
reproducible. Big data science, including simulation research, cannot depend exclusively on …