Understanding the genetic basis of variation in meiotic recombination: past, present, and future

SE Johnston - Molecular Biology and Evolution, 2024 - academic.oup.com
Meiotic recombination is a fundamental feature of sexually reproducing species. It is often
required for proper chromosome segregation and plays important role in adaptation and the …

From molecules to populations: appreciating and estimating recombination rate variation

JV Peñalba, JBW Wolf - Nature Reviews Genetics, 2020 - nature.com
Recombination is a central biological process with implications for many areas in the life
sciences. Yet we are only beginning to appreciate variation in the recombination rate along …

Genomes of the mouse collaborative cross

A Srivastava, AP Morgan, ML Najarian, VK Sarsani… - Genetics, 2017 - academic.oup.com
Abstract The Collaborative Cross (CC) is a multiparent panel of recombinant inbred (RI)
mouse strains derived from eight founder laboratory strains. RI panels are popular because …

Plant tolerance to drought stress with emphasis on wheat

S Adel, N Carels - Plants, 2023 - mdpi.com
Environmental stresses, such as drought, have negative effects on crop yield. Drought is a
stress whose impact tends to increase in some critical regions. However, the worldwide …

Leveraging a phased pangenome for haplotype design of hybrid potato

L Cheng, N Wang, Z Bao, Q Zhou, A Guarracino… - Nature, 2025 - nature.com
The tetraploid genome and clonal propagation of the cultivated potato (Solanum tuberosum
L.), dictate a slow, non-accumulative breeding mode of the most important tuber crop …

Natural selection shapes variation in genome-wide recombination rate in Drosophila pseudoobscura

K Samuk, B Manzano-Winkler, KR Ritz, MAF Noor - Current Biology, 2020 - cell.com
While recombination is widely recognized to be a key modulator of numerous evolutionary
phenomena, we have a poor understanding of how recombination rate itself varies and …

Megabase-scale presence-absence variation with Tripsacum origin was under selection during maize domestication and adaptation

Y Huang, W Huang, Z Meng, GT Braz, Y Li, K Wang… - Genome biology, 2021 - Springer
Abstract Background Structural variants (SVs) significantly drive genome diversity and
environmental adaptation for diverse species. Unlike the prevalent small SVs (< kilobase …

[PDF][PDF] Divergent fine-scale recombination landscapes between a freshwater and marine population of threespine stickleback fish

AF Shanfelter, SL Archambeault… - Genome biology and …, 2019 - academic.oup.com
Meiotic recombination is a highly conserved process that has profound effects on genome
evolution. At a fine-scale, recombination rates can vary drastically across genomes, often …

Peyer's patch TH17 cells are dispensable for gut IgA responses to oral immunization

I Gribonika, A Strömberg, C Lebrero-Fernandez… - Science …, 2022 - science.org
T helper 17 (TH17) cells located at the Peyer's patch (PP) inductive site and at the lamina
propria effector site of the intestinal immune system are responsive to both pathogenic and …

Genetic drivers of pancreatic islet function

MP Keller, DM Gatti, KL Schueler, ME Rabaglia… - Genetics, 2018 - academic.oup.com
The majority of gene loci that have been associated with type 2 diabetes play a role in
pancreatic islet function. To evaluate the role of islet gene expression in the etiology of …