For several decades, serum levels of alanine (ALT) and aspartate (AST) aminotransferases
have been regarded as markers of liver injury, including a wide range of etiologies from viral …

Cardiometabolic diseases are the leading cause of death worldwide and are strongly linked
to both genetic and nutritional factors. The field of nutrigenomics encompasses multiple …

Rationale: Activation of the mitochondrial ATP-sensitive potassium channel (mitoKATP) has
been implicated in the mechanism of cardiac ischemic preconditioning, yet its molecular …

SARS-CoV-2 infection causes COVID-19, a severe acute respiratory disease associated
with cardiovascular complications including long-term outcomes. The presence of virus in …

The circulatory system of Drosophila melanogaster represents an easily amenable genetic
model whose analysis at different levels, ie, from single molecules up to functional anatomy …

Because proteins are the major functional components of cells, knowledge of their cellular
localization is crucial to gaining an understanding of the biology of multicellular organisms …

The syndecans are the major family of transmembrane proteoglycans, usually bearing
multiple heparan sulfate chains. They are present on virtually all nucleated cells of …

Over the past three-decades, Janus kinase (Jak) and signal transducer and activator of
transcription (STAT) signaling has emerged as a paradigm to understand the involvement of …

Congenital heart diseases (CHDs), including hypoplastic left heart syndrome (HLHS), are
genetically complex and poorly understood. Here, a multidisciplinary platform was …

The human heart is capable of functioning for decades despite minimal cell turnover or
regeneration, suggesting that molecular alterations help sustain heart function with age …