Flow-induced reprogramming of endothelial cells in atherosclerosis

IA Tamargo, KI Baek, Y Kim, C Park, H Jo - Nature Reviews Cardiology, 2023 - nature.com
Atherosclerotic diseases such as myocardial infarction, ischaemic stroke and peripheral
artery disease continue to be leading causes of death worldwide despite the success of …

The role of infiltrating immune cells in dysfunctional adipose tissue

TJ Guzik, DS Skiba, RM Touyz… - Cardiovascular …, 2017 - academic.oup.com
Adipose tissue (AT) dysfunction, characterized by loss of its homeostatic functions, is a
hallmark of non-communicable diseases. It is characterized by chronic low-grade …

Stent thrombosis and restenosis with contemporary drug-eluting stents: predictors and current evidence

F Condello, C Spaccarotella, S Sorrentino… - Journal of clinical …, 2023 - mdpi.com
Iterations in stent technologies, advances in pharmacotherapy, and awareness of the
implications of implantation techniques have markedly reduced the risk of stent failure, both …

circ-Sirt1 controls NF-κB activation via sequence-specific interaction and enhancement of SIRT1 expression by binding to miR-132/212 in vascular smooth muscle …

P Kong, Y Yu, L Wang, YQ Dou, XH Zhang… - Nucleic acids …, 2019 - academic.oup.com
NF-κB-mediated inflammatory phenotypic switching of vascular smooth muscle cells
(VSMCs) plays a central role in atherosclerosis and neointimal formation. However, little is …

Placental formation in early pregnancy: how is the centre of the placenta made?

AL Boss, LW Chamley, JL James - Human reproduction update, 2018 - academic.oup.com
BACKGROUND Correct development of the placenta is critical to establishing pregnancy
and inadequate placentation leads to implantation failure and miscarriage, as well as later …

MicroRNA regulation of phenotypic transformations in vascular smooth muscle: relevance to vascular remodeling

G Wang, Y Luo, X Gao, Y Liang, F Yang, J Wu… - Cellular and Molecular …, 2023 - Springer
Alterations in the vascular smooth muscle cells (VSMC) phenotype play a critical role in the
pathogenesis of several cardiovascular diseases, including hypertension, atherosclerosis …

The multifactorial nature of microRNAs in vascular remodelling

SMJ Welten, EAC Goossens, PHA Quax… - Cardiovascular …, 2016 - academic.oup.com
Vascular remodelling is a multifactorial process that involves both adaptive and maladaptive
changes of the vessel wall through, among others, cell proliferation and migration, but also …

Role of flow-sensitive microRNAs and long noncoding RNAs in vascular dysfunction and atherosclerosis

S Kumar, D Williams, S Sur, JY Wang, H Jo - Vascular pharmacology, 2019 - Elsevier
Atherosclerosis is the primary underlying cause of myocardial infarction, ischemic stroke,
and peripheral artery disease. The disease preferentially occurs in arterial regions exposed …

MicroRNAs for restenosis and thrombosis after vascular injury

C Gareri, S De Rosa, C Indolfi - Circulation research, 2016 - ahajournals.org
Percutaneous revascularization revolutionized the therapy of patients with coronary artery
disease. Despite continuous technical advances that substantially improved patients' …

Epigenetics and immunometabolism in diabetes and aging

TJ Guzik, F Cosentino - Antioxidants & redox signaling, 2018 - liebertpub.com
Significance: A strong relationship between hyperglycemia, impaired insulin pathway, and
cardiovascular disease in type 2 diabetes (T2D) is linked to oxidative stress and …