Advances in engineering human tissue models
Research in cell biology greatly relies on cell-based in vitro assays and models that facilitate
the investigation and understanding of specific biological events and processes under …
the investigation and understanding of specific biological events and processes under …
Biomaterials for skin substitutes
Patients with extensive burns rely on the use of tissue engineered skin due to a lack of
sufficient donor tissue, but it is a challenge to identify reliable and economical scaffold …
sufficient donor tissue, but it is a challenge to identify reliable and economical scaffold …
[HTML][HTML] Exosomes derived from platelet-rich plasma promote the re-epithelization of chronic cutaneous wounds via activation of YAP in a diabetic rat model
SC Guo, SC Tao, WJ Yin, X Qi, T Yuan, CQ Zhang - Theranostics, 2017 - ncbi.nlm.nih.gov
Chronic wounds have become an economic, social, and public health burden and need
advanced treatment. Platelet-rich plasma (PRP) has been used extensively in treatment of …
advanced treatment. Platelet-rich plasma (PRP) has been used extensively in treatment of …
Highly elastic and conductive human-based protein hybrid hydrogels
Elastomers are key components of many natural systems including organisms' organs. In
addition, elastomeric polymer-based materials have been used for various applications such …
addition, elastomeric polymer-based materials have been used for various applications such …
Hydrogel-based strategies to advance therapies for chronic skin wounds
Chronic skin wounds are the leading cause of nontraumatic foot amputations worldwide and
present a significant risk of morbidity and mortality due to the lack of efficient therapies. The …
present a significant risk of morbidity and mortality due to the lack of efficient therapies. The …
Tailoring the porosity and pore size of electrospun synthetic human elastin scaffolds for dermal tissue engineering
We obtained low and high porosity synthetic human elastin scaffolds by adapting low (1
mL/h) and high (3 mL/h) flow rates respectively during electrospinning. Physical, mechanical …
mL/h) and high (3 mL/h) flow rates respectively during electrospinning. Physical, mechanical …
Increasing the pore size of electrospun scaffolds
J Rnjak-Kovacina, AS Weiss - Tissue Engineering Part B: Reviews, 2011 - liebertpub.com
Electrospinning has gained much attention in the past decade as an effective means of
generating nano-to micro-scale polymer fibers that resemble native extracellular matrix …
generating nano-to micro-scale polymer fibers that resemble native extracellular matrix …
Nanoscale engineering of biomimetic surfaces: cues from the extracellular matrix
K von der Mark, J Park, S Bauer, P Schmuki - Cell and tissue research, 2010 - Springer
The ultimate goal in the design of biomimetic materials for use in tissue engineering as
permanent or resorbable tissue implants is to generate biocompatible scaffolds with …
permanent or resorbable tissue implants is to generate biocompatible scaffolds with …
A multilayered synthetic human elastin/polycaprolactone hybrid vascular graft with tailored mechanical properties
Small-diameter synthetic vascular graft materials fail to match the patency of human tissue
conduits used in vascular bypass surgery. The foreign surface retards endothelialization and …
conduits used in vascular bypass surgery. The foreign surface retards endothelialization and …
Hydrogel scaffolds as in vitro models to study fibroblast activation in wound healing and disease
ME Smithmyer, LA Sawicki, AM Kloxin - Biomaterials science, 2014 - pubs.rsc.org
Wound healing results from complex signaling between cells and their environment in
response to injury. Fibroblasts residing within the extracellular matrix (ECM) of various …
response to injury. Fibroblasts residing within the extracellular matrix (ECM) of various …