Drug discovery is adapting to novel technologies such as data science, informatics, and
artificial intelligence (AI) to accelerate effective treatment development while reducing costs …

Extensive research links regular physical exercise to an overall enhancement of cognitive
function across the lifespan. Here we assess the causal evidence supporting this …

We conducted the Reproducibility Project: Cancer Biology to investigate the replicability of
preclinical research in cancer biology. The initial aim of the project was to repeat 193 …

How good a research scientist is ChatGPT? We systematically probed the capabilities of
GPT-3.5 and GPT-4 across four central components of the scientific process: as a Research …

From vaccination refusal to climate change denial, antiscience views are threatening
humanity. When different individuals are provided with the same piece of scientific evidence …

Empirical observations of how labs conduct research indicate that the adoption rate of open
practices for transparent, reproducible, and collaborative science remains in its infancy. This …

The emergence of large-scale replication projects yielding successful rates substantially
lower than expected caused the behavioural, cognitive, and social sciences to experience a …

Recent years have marked a renaissance in efforts to increase research reproducibility in
psychology, neuroscience, and related fields. Reproducibility is the cornerstone of a solid …

Known methodological issues such as publication bias, questionable research practices
and studies with underpowered designs are known to decrease the replicability of study …

Metal ions bound to macromolecules play an integral role in many cellular processes. They
can directly participate in catalytic mechanisms or be essential for the structural integrity of …