Conspectus Securinega alkaloids, composed of more than 100 members characterized by
the compact tetracyclic scaffold, have fascinated the synthetic community with their structural …

Recent advances in synthetic methodologies for selective, oxidative transformations using
Bobbitt's salt (4-acetamido-2, 2, 6, 6-tetramethyl-1-oxopiperidinium tetrafluoroborate, 1) and …

Covering: up to the end of July, 2023 1, 2-Oxazine is a heterocyclic scaffold rarely found in
natural products and is characterized by a directly connected N–O bond in a six-membered …

A Pd-catalyzed C–O cross-coupling of O-acyl hydroxylamines and tertiary or secondary alkyl
electrophiles was reported without the cleavage of the rather fragile N–O bond. The …

We completed the synthesis of dimeric high-oxidation-state securinega alkaloid
flueggeacosine B via two synthetic routes from allosecurinine. The first-generation synthesis …

Herein we describe a total synthesis of the heterodimeric securinega alkaloid (−)-
flueggeacosine C (8). The convergent synthetic strategy is based on a Liebeskind–Srogl …

Catalytic reduction of oximes represents a direct efficient approach to synthesize valuable
hydroxylamine derivatives. However this transformation presents significant challenges …

An Fe-catalyzed unprotected hydroxylamine mediated Heck-type coupling between sulfinic
acids and alkenes for the regioselective synthesis of (E)-vinyl sulfones has been developed …

Natural products are the most effective source of potential drug leads. The total synthesis of
bioactive natural products plays a crucial role in confirming the hypothetical complex …

We found that cyclometalated cyclopentadienyl iridium (III) complexes are uniquely efficient
catalysts in homogeneous hydrogenation of oximes to hydroxylamine products. A stable …